Results 101 to 110 of about 32,488 (260)

Bringing to disciplinary responsibility of employees and employers on labor law

open access: yesUniversidad y Sociedad, 2018
The work deals with the issues of attracting employees and managers to material liability for inflicting last damage on the employer, and the regulation of the provisions on the liability of the parties to the employment contract. The objectives of labor
Kseniya E. Kovalenko   +2 more
doaj  

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

open access: yesAdvanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou   +4 more
wiley   +1 more source

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine from Xylose in Escherichia coli

open access: yesAdvanced Science, EarlyView.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han   +5 more
wiley   +1 more source

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang   +13 more
wiley   +1 more source

Control Responsibility: The Discursive Construction of Privacy, Teens, and Facebook in Flemish Newspapers

open access: yesInternational Journal of Communication, 2019
This study explores the discursive construction of online privacy through a critical discourse analysis of Flemish newspapers’ coverage of privacy, teens, and Facebook between 2007 and 2018 to determine what representation of (young) users the papers ...
Ralf De Wolf, Stijn Joye
doaj   +2 more sources

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

open access: yesAdvanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang   +12 more
wiley   +1 more source

A Laminating Strategy to Manyfold Enhance the Elastic Stretchability of Stretchable Electronics

open access: yesAdvanced Science, EarlyView.
We propose a laminating strategy that laminates a thick‐polymer layer onto the thin‐ribbon metallic structure. Using serpentine structures on soft and hard substrates as representative cases, this approach increases elastic stretchability by 3.5‐fold and 2.3‐fold.
Zanxin Zhou   +6 more
wiley   +1 more source

SPECIAL DISCIPLINARY RESPONSIBILITY: FEATURES OF REGULATORY REGULATION

open access: yesJuridical scientific and electronic journal, 2022
L.O. Vasechko, V.O. Shevchenko
openaire   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li   +16 more
wiley   +1 more source

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