Results 91 to 100 of about 67,482 (304)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Study on Business English Discipline Construction

open access: yesProceedings of the 2013 International Conference on Educational Research and Sports Education, 2013
This paper first investigates the theoretical foundation of business English discipline construction in our country and then discusses the necessity of business English discipline construction. Then, the paper presents a few issues to be noted in the process of business English discipline construction.
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Understanding Construction Supply Chains: An Alternative Interpretation [PDF]

open access: yes
Much research work has assessed that construction is ineffective and many problems can be observed. Analysis of these problems has shown that a major part of them are supply chain problems, originating at the interfaces of different parties or functions.
Koskela, Lauri   +2 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Mapping the Construction Engineering and Management Discipline [PDF]

open access: yes, 2003
The objective of the study was to map the structure of the construction engineering and management (CEM) discipline and its contents, trace its evolution, and to identify the most prevailing research areas in the discipline.
Aboulezz, Mohamed A
core  

WeChat dual-group (mis-)use: a qualitative exploration of Chinese undergraduate students’ use of mobile social media applications and its pedagogical implications

open access: yesFrontiers in Psychology
IntroductionAlthough WeChat is widely adopted in Chinese higher-education English-translation programmes, little is known about how students actually use its group-chat function for collaborative learning or what problems arise.
Yuanxing Tan, Ran Ren
doaj   +1 more source

以脑血管病为特色神经病学学科建设的探索与实践 Exploration and Practice of Neurology Discipline Construction Characterized by Cerebrovascular Disease

open access: yesZhongguo cuzhong zazhi, 2019
首都医科大学附属北京天坛医院从建立神经内科,搭建神经病学学科建设平台的过程中, 以脑血管病为中心,全面发展神经病学各个亚专业,创建了包括多个神经科学相关临床专业、临床和 基础研究、统计学在内的神经病学中心。本文介绍了天坛医院瞄准国际前沿脉动,创新发展各个学科, 注重青年人才培养,在基础和临床研究领域做出了国际一流的突出成绩,改写国际指南,使得神经病 学科全面发展,其卓有成效的发展模式为全国神经病学中心建设和人才培养提供了典范和经验。 Abstract: This paper introduced
朱丽丽,赵性泉,王春雪,杜万良,王拥军
doaj   +1 more source

[First-Class Nursing Discipline Construction Spearheads the Cultivation of First-Class Talents]. [PDF]

open access: yesSichuan Da Xue Xue Bao Yi Xue Ban, 2023
Hu YJ   +6 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy