Results 81 to 90 of about 7,451,038 (316)

Multidimensional Challenges and Development Strategies in the Construction of Rare Disease Discipline

open access: yes罕见病研究
The development of the rare disease discipline is a crucial pathway for enhancing the diagnosis and treatment of rare diseases, cultivating specialized professionals, and fostering technological innovation.
GONG Li   +4 more
doaj   +1 more source

DesignWorld : a tool for team collaboration in high band\ud virtual environments [PDF]

open access: yes, 2005
Current software tools for documenting and developing models of buildings focus on supporting a\ud single user who is a specialist in the specific software used within their own discipline.

core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Introduction to cyberspace security discipline

open access: yes网络与信息安全学报, 2019
With rapidly development of electronic information technology and industry,human society comes into information age.In the information age human lives and works in cyberspace.There for,it is the base requirement for human to ensure cyberspace security in
Huanguo ZHANG, Ruiying DU
doaj   +3 more sources

Exploring the impact of ICT interaction on students’ creative thinking across performance levels: an explainable AI perspective

open access: yesFrontiers in Psychology
This study uses the PISA 2022 ICT questionnaire to examine how students’ ICT interaction behaviours in digital environments predict creative thinking across low, medium, and high performance levels (Class 0–2).
Xinhai Cai   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Guided by National Strategic Needs, Striving to Build a First-Class Forensic Medicine Discipline — The Construction Plan for Forensic Medicine at Southern Medical University

open access: yesFayixue Zazhi
The 2024 National Education Work Conference pointed out that at the current juncture of the critical period for achieving the goals and tasks of the 14th Five-Year Plan, the implementation of the Education Powerhouse Construction Plan Outline should be ...
QIAO Dong-fang   +8 more
doaj   +1 more source

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