Results 111 to 120 of about 4,637,860 (323)

Construction History in Spain

open access: yes, 2015
En Espagne, l’histoire de la construction constitue une discipline à part entière, consolidée durant ces vingt dernières années en raison des nombreuses manifestations dédiées. Mais des obstacles pourraient la menacer : l’absence d’enseignement, l’amateurisme et la fragmentation. L’enseignement est envisagé dès la formation initiale.
Huerta Fernández, Santiago   +1 more
openaire   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Thoughts on the Development of Forensic Medicine Discipline Standing at a New Historical Starting Point

open access: yesFayixue Zazhi
The development of forensic medicine is crucial to the national welfare, people’s livelihood, social stability, and the construction of a Safe China. It plays an indispensable role in the comprehensive promotion of the rule of law.
LI Cheng-tao, CONG Bin
doaj   +1 more source

Fostering Emotional Engineers: Revisiting Constructive Thinking in Engineering Education [PDF]

open access: yes, 2020
For the past decade, engineering education efforts at the postsecondary level have sought to create a more holistic type of critical thinker (Felder & Brent, 2015; Grasso & Burkins, 2010).
Arce-Trigatti, Andrea
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Analysis of Vibration Transmission Path in Packaging System and Design of Teaching Experiment

open access: yesShock and Vibration
It is essential for realizing the most suitable product buffer packaging design to quantify the vibration transmission characteristics of the product packaging system.
Meilin Gong, Cong Lin
doaj   +1 more source

Seventy Years of Passing on the Torch, Striving Forward in the New Era — Thoughts on the Construction of Forensic Medicine at Sun Yat-sen University

open access: yesFayixue Zazhi
The forensic medicine discipline of Sun Yat-sen University is one of the important origins of modern and contemporary forensic medicine education in China, and it is a microcosm of the development of forensic medicine education, research and ...
SUN Hong-yu, ZHAO Hu
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The functions of visual management [PDF]

open access: yes, 2009
Visual Management has been evolving and effectively employed in some manufacturing and service organisations for a long time. In order to facilitate a cross-industrial learning process and to advance in detailed research the understanding of how the ...
Koskela, LJ, Tezel, BA, Tzortzopoulos, P
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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