Results 121 to 130 of about 66,969 (302)

Shouldering the Responsibility of Building a Law-Based China and Advancing the Comprehensive Development of Forensic Clinical Medicine

Fayixue Zazhi
The forensic clinical discipline in China has evolved from early practices of living body examination into a dedicated framework featuring a complete bachelor, master and doctoral education system, a professional forensic identification workforce, and a ...
DENG Zhen-hua
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Reflections on the Discipline Construction Environment of World Literature and Comparative Literature in the Era of Big Data Analysis.

J Environ Public Health, 2022
Xu W.
europepmc   +1 more source

Understanding Construction Supply Chains: An Alternative Interpretation

Much research work has assessed that construction is ineffective and many problems can be observed. Analysis of these problems has shown that a major part of them are supply chain problems, originating at the interfaces of different parties or functions.
Koskela, Lauri, Vrijhoef, Ruben, Howell, Greg   +2 more
core  

EX ANTE CONSTRUCTION COSTS IN THE EUROPEAN ROAD SECTOR: A COMPARISON OF PUBLIC-PRIVATE PARTNERSHIPS AND TRADITIONAL PUBLIC PROCUREMENT [PDF]

Theoretical literature suggests a variety of reasons why a public-private partnership (PPP)should exhibit higher costs of construction than traditionally procured public infrastructure projects.
Blanc-Brude, Frederic, Valila, Timo, Goldsmith, Hugh   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Discipline Construction and Development of Medical Universities in Complex Environment under Digital Technology and Structural Equation Model.

J Healthc Eng, 2022
Ge B, Ma W, Ji J.
europepmc   +1 more source

Mapping the Construction Engineering and Management Discipline

, 2003
The objective of the study was to map the structure of the construction engineering and management (CEM) discipline and its contents, trace its evolution, and to identify the most prevailing research areas in the discipline.
Aboulezz, Mohamed A
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Fields of Discipline Construction [PDF]

Proceedings of the 2nd International Conference on Judicial, Administrative and Humanitarian Problems of State Structures and Economic Subjects (JAHP 2017), 2017
openaire   +1 more source