Results 81 to 90 of about 88,827 (261)

Propofol-Associated Urine Discoloration: Systematic Literature Review

, 2023
Propofol occasionally induces a green or pink-cloudy urine discoloration. A lesser-known effect is green discoloration of hair, milk, liver, or stool. We aimed to gain insight into the features of these disturbances. The terms ("propofol" OR "fospropofol"
Bianchetti, M.G., Cinzia Cortesi, Lava, SAG, Gregorio P. Milani, Schera, F.M., Lasica, A., Federica M. Schera, Pietro Camozzi, Milani, G.P., Camozzi, P., Sebastiano A.G. Lava, Cortesi, C., Ana Lasica, Mario G. Bianchetti, Camozzi P., Cortesi C., Bianchetti M. G., Milani G. P., Lava S. A. G., Lasica A., Schera F. M.   +20 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Marginal discoloration at the 12-month clinical follow-up examination.

, 2018
Marginal discoloration at the 12-month clinical follow-up examination.
Any de Castro Ruiz Marques (4872079), Uhana Seifert Guimarães Suga (641403), Laíse Midori Tokubo (4872085), Renata Corrêa Pascotto (641407), Marcelo Giannini (4827189), Paula de Castro Kruly (4872082), Raquel Sano Suga Terada (641404)   +6 more
core   +1 more source

Tobacco-associated yellow discoloration of upper lip hair: smoker's mustache [PDF]

, 2015
Background: Hair is susceptible to exogenous sources of discoloration. There are several exogenous etiologies for yellow hair discoloration, including tobacco.Purpose: We describe the clinical features of five men with tobacco-associated yellow ...
Beutler, Bryce D, Cohen, Philip R, Beutler, Bryce D ; Cohen, Philip R, Bryce D Beutler, Philip R Cohen   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Marginal discoloration at the 24-month clinical follow-up examination.

, 2018
Marginal discoloration at the 24-month clinical follow-up examination.
Any de Castro Ruiz Marques (4872079), Uhana Seifert Guimarães Suga (641403), Laíse Midori Tokubo (4872085), Renata Corrêa Pascotto (641407), Marcelo Giannini (4827189), Paula de Castro Kruly (4872082), Raquel Sano Suga Terada (641404)   +6 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The role of chromogenic bacteria in external tooth discoloration in children

, 2016
Tooth discoloration can cause social and psychological problems and lead to loss of self-confidence in children. Concerns of parents and children on appearance and esthetics increase the importance of dental esthetic treatments in children.
Zuhal Kırzıoğlu, Burcu Güçyetmez Topal   +1 more
core   +1 more source

Visual inspection of Type D modules showed: (a) discoloration near the cell edges, (b) & (c) discoloration of EVA & burn marks on the Si-cells.

, 2022
Visual inspection of Type D modules showed: (a) discoloration near the cell edges, (b) & (c) discoloration of EVA & burn marks on the Si-cells.
Haseeb Ahmad Khan (11820017), Adnan Daud Khan (11820014), Shanshan Tu (623574), Obaid ur Rehman (11820020), Muhammad Noman (4266664), Fahad Ullah Zafar (11973403), Sadaqat Ur Rehman (11973406), Muhammad Waqas (535011), Shahab Ahmad (1261248)   +8 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source