Results 141 to 150 of about 201,347 (283)

Risk‐aware safe reinforcement learning for control of stochastic linear systems

open access: yesAsian Journal of Control, EarlyView.
Abstract This paper presents a risk‐aware safe reinforcement learning (RL) control design for stochastic discrete‐time linear systems. Rather than using a safety certifier to myopically intervene with the RL controller, a risk‐informed safe controller is also learned besides the RL controller, and the RL and safe controllers are combined together ...
Babak Esmaeili   +2 more
wiley   +1 more source

Regional Shopping Objectives in British Grocery Retail Transactions Using Segmented Topic Models

open access: yesApplied Stochastic Models in Business and Industry, EarlyView.
ABSTRACT Understanding the customer behaviours behind transactional data has high commercial value in the grocery retail industry. Customers generate millions of transactions every day, choosing and buying products to satisfy specific shopping needs.
Mariflor Vega Carrasco   +4 more
wiley   +1 more source

A general theory of time discounting: The reference-time theory of intertemporal choice [PDF]

open access: yes
We develop a general theory of intertemporal choice: the reference-time theory, RT. RT is a synthesis of ideas from the generalized hyperbolic model (Loewenstein and Prelec 1992), the quasi-hyperbolic model (Phelps and Pollak 1968, Laibson 1997) and ...
Ali al-Nowaihi, Sanjit Dhami
core  

Simulating competition in the US bioeconomy to produce hard‐to‐electrify transportation fuels using limited biomass resources

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study presents a novel bioeconomy optimization framework, BiOpt, designed to address critical questions regarding the strategic use of limited US biomass resources for biofuel production. By integrating detailed techno‐economic analyses, life cycle assessments, and resource assessment data, BiOpt optimizes resource distributions across ...
Nicholas A. Carlson   +3 more
wiley   +1 more source

Fat Debtors: Time Discounting, Its Anomalies, and Body Mass Index [PDF]

open access: yes
In view of the finding that debtors are likely to be more obese than nondebtors, we investigate whether interpersonal differences in body mass are, as in the case of debt behavior, related to those in time discounting and time discounting anomalies.
Fumio Ohtake   +2 more
core  

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Should we discount future generations’ welfare? A survey on the “pure” discount rate debate. [PDF]

open access: yes
In A Mathematical Theory of Saving (1928), Frank Ramsey not only laid the foundations of the fruitful optimal growth literature, but also launched a major moral debate: should we discount future generations’ well-being?
Grégory Ponthière
core  

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Impatience and Intergenerational Equity in a Model of Sustainable Growth [PDF]

open access: yes
We argue that intergenerational neutrality has been prematurely excluded from the dialogue on sustainable growth. By incorporating Burton’s distinction between intragenerational and intergenerational discounting into a model suitable for analyzing ...
Basharat Pitafi   +3 more
core  

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy