Results 51 to 60 of about 355,328 (237)

Building professional discourse in emerging markets: Language, context and the challenge of sensemaking [PDF]

open access: yes, 2013
Using ethnographic evidence from the former Soviet republics, this article examines a relatively new and mainly unobserved in the International Business (IB) literature phenomenon of communication disengagement that manifests itself in many emerging ...
A Denzau   +90 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

From discourse to effectiveness: A communication studies perspective on college counselors' individual psychological counseling

open access: yesActa Psychologica
College counselors are central to students' mental health education, where effective discourse is crucial for successful individual counseling. Yet, most studies emphasize counseling content or student attitudes, with limited empirical analysis of how ...
Haimei Zheng, Qing Feng, Guibin Wang
doaj   +1 more source

Native speaker-non-native speaker interaction: the use of discourse makers [PDF]

open access: yes, 2001
Discourse markers have a basic role in oral interactions. Apart from providing coherence and regulating turn-taking, they have important interactive functions that indicate the conversational commitment and the social behaviour of the interlocutors in an
Iglesias Moreno, Ángela Eugenia
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Theorising tertiary writing instruction: Accounting for the process, post-process, genre and critical literacies approaches [PDF]

open access: yes, 2008
This discussion of theories of writing instruction arises from the context of teaching research writing to postgraduate students for whom English is an additional language.
Bruce, Ian
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

International student subjectivities: biographical investments for liquid times [PDF]

open access: yes, 2005
The international student as an object of study has typically been understood through the frame of cultural identity, mapped back to notions of fixed, static notions of cultural difference.
Doherty, Catherine A., Singh, Parlo
core   +1 more source

Avoiding initiation of repair in L2 conversations-for-learning [PDF]

open access: yes, 2017
Using audio-recorded data from second language (L2) English conversations-for-learning between an L2 user of English and a first language (L1) user of English (the researcher), this study analyzes cases in which the L1 user avoids initiation of repair ...
Eric Hauser
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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