Results 101 to 110 of about 169,123 (346)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Conditional converb of the verb ‘say’ as a conditional marker in Forest Enets

open access: yesEesti ja Soome-ugri Keeleteaduse Ajakiri
In Forest Enets conditional constructions, the protasis clause is typically headed by a conditional converb. The conditional converb of the verb man- ‘say’ also serves as a conditional marker in the form mab or mabut, which is typically used along ...
Maria Ovsjannikova
doaj   +1 more source

Jæʕne dans le discours des Libanais : pragmaticalisation, distribution et emplois d’un marqueur discursif déverbal

open access: yesDiscours, 2013
This paper deals with jæʕne, a Lebanese discourse marker (also used by Syrian, Palestinian and Egyptian speakers). Jæʕne can be translated as it means, that is to say, I mean, you mean, or even by a filled pause.
Layal Kanaan
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

De l’adverbe de manière au marqueur discursif : le cas de autrement [PDF]

open access: yesStudii de Lingvistica, 2019
The present research focuses on the French adverb autrement, which is characterized by a wide range of uses. This allows it to function not only as an adverb of manner that modifies the verb, but also as a discourse marker that the speaker employs to ...
Céline Corteel
doaj  

Nominalization and focus constructions in some Kiranti languages [PDF]

open access: yes, 2010
It is well-known that in many if not most Sino-Tibetan languages relative clause and attribute/genitive markers are identical with nominalization devices and that sentences bearing such markers can also function as independent utterances (cf.
Bickel, Balthasar
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

'Should conditionals be emergent ...': asyndetic conditionals in English and German as a Challenge to Grammaticalization Research [PDF]

open access: yes, 2010
The present article examines asyndetic or conjunctionless conditionals in German and English. According to Jespersen’s Model (1940), this construction arose diachronically from a paratactic discourse sequence with a polar interrogative, but more recently
Van den Nest, Daan
core   +1 more source

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