Results 111 to 120 of about 207,019 (347)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Domains and Functions: A Two-Dimensional Account of Discourse Markers
Discourse markers and their functions have been modeled through a large number of very diverse frameworks. Most of these models target written language and the discourse relations that hold between sentences. In this paper, we present, assess and apply a
Ludivine Crible, Liesbeth Degand
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Importance marking: Giving reference to the highlighted discourse in academic lectures [PDF]
This study was an attempt to explore how important points are highlighted in Persian academic lectures. More specifically, this paper was aimed to reach a taxonomy of importance markers based on (a) the discourse functions of importance markers, and (b ...
Javad Zare , Keivanloo-Shahrestanaki
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Relational Practice in Multilingual Peer Discourse: Talk as a Marker of Gender Identity
Rabia Faiz +2 more
openalex +2 more sources
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
O tratamento de marcadores discursivos em uma ferramenta de apoio à escrita acadêmica em português para nativos de espanhol [PDF]
We report in this paper the development of a module dedicated to discourse markers in HABLA (Hispanofalantes Purchasing an Academic Lin-guistic Base), a tool designed to support native Spanish speakers in their aca-demic writing in Portuguese.
Aluisio, Sandra Maria +2 more
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