Results 101 to 110 of about 11,790 (293)

Interface between conjugal violence and alcohol consumption by the partner

Revista Brasileira de Enfermagem
Objective: to analyze the discourse of women on the interface between marital violence and alcohol use by the partner. Method: qualitative exploratory research, based on the methodological reference of oral history.
Milca Ramaiane da Silva Carvalho, Jeane Freitas de Oliveira, Nadirlene Pereira Gomes, Mariana Matias Santos, Fernanda Matheus Estrela, Helenise Maria da Silva Duarte   +5 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

The Affective Configuration of the Public Problem of Depopulation: From Resignation to Obstinance

Communication & Society (Formerly Comunicación y Sociedad)
Participation in public problems involves diverse strategies, including the challenging and transformation of hegemonic affective configurations.
Vanesa Saiz-Echezarreta
doaj   +1 more source

SURPRISING PEREGRINATIONS AND RELATIONSHIPS OF CONCEPTS. ON THE THOUGHT COLLECTIVE OF LUDWIK FLECK AND THE INTERPRETIVE COMMUNITY OF STANLEY FISH [PDF]

Filozofia i Nauka, 2019
The aim of the article is to compare the thought collective and the interpretive community, two surprisingly similar notions formulated independently by Ludwik Fleck and Stanley Fish.
Marzenna Cyzman
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Naturalization, reciprocity and marks of marital violence: male defendants' perceptions

Revista Brasileira de Enfermagem
Objective: to analyze male criminals' perception about marital violence. Method: An exploratory, descriptive, qualitative study undertaken with 23 men who were criminally prosecuted for marital violence. A multimethod data collection was conducted, with
Gilvânia Patrícia do Nascimento Paixão, Alvaro Pereira, Nadirlene Pereira Gomes, Anderson Reis de Sousa, Fernanda Matheus Estrela, Ubirajara Ramos Pereira da Silva Filho, Igor Brasil de Araújo   +6 more
doaj   +1 more source

Religiosity in the work of cancer care nurses and its meaning from the perspective of collective subject discourse

, 2007
Religion can serve as an instrument to motivate and support health professionals in the development and improvement of their technical skills with patients. The current study focused on the significance of religious faith in routine work by nurses and the meaning they ascribe to religious faith in the treatment and lives of elderly cancer patients. The
Teixeira, Jorge Juarez Vieira, Lefèvre, Fernando   +1 more
openaire   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source