Results 91 to 100 of about 15,467,312 (299)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Reduced–Order Perfect Nonlinear Observers of Fractional Descriptor Discrete–Time Nonlinear Systems

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2017
The purpose of this work is to propose and characterize fractional descriptor reduced-order perfect nonlinear observers for a class of fractional descriptor discrete-time nonlinear systems.
Kaczorek Tadeusz
doaj   +1 more source

Asymptotic results for the first and second moments and numerical computations in discrete-time bulk-renewal process [PDF]

open access: yesYugoslav Journal of Operations Research, 2019
This paper introduces a simplified solution to determine the asymptotic results for the renewal density. It also offers the asymptotic results for the first and second moments of the number of renewals for the discrete-time bulk-renewal process.
Kim James J.   +2 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Positivity of Fractional Descriptor Linear Discrete–Time Systems

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2019
The positivity of fractional descriptor linear discrete-time systems is investigated. The solution to the state equation of the systems is derived. Necessary and sufficient conditions for the positivity of fractional descriptor linear discrete-time ...
Kaczorek Tadeusz
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Robust Stability Analysis of Switching Time-Delay Systems via a Novel Non-Monotonic Lyapunov–Krasovskii Approach [PDF]

open access: yesInternational Journal of Research and Technology in Electrical Industry
In this paper, a novel approach based on a non-monotonic Lyapunov–Krasovskii functional is first proposed for the comprehensive stability analysis of discrete-time switched systems with time delays in an m-step-ahead scheme.
Saeed Ahmadi, Younes Solgi
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Group Consensus of Mixed-Order Multi-Agent Systems With Fixed and Directed Interactive Topology

open access: yesIEEE Access, 2019
This paper studies the group consensus of discrete-time mixed-order multi-agent systems with fixed and directed interactive topology. First, group consensus protocols are designed for all agents to investigate the group consensus of mixed-order multi ...
Min Liu, Yuanzhen Feng
doaj   +1 more source

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