Results 81 to 90 of about 15,467,312 (299)

Non-linear discrete-time observer design by sliding mode [PDF]

open access: yes, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 09/02/2007.Research into observer design for non-linear discrete-time systems has produced many design methods.
Algarawi, Mohammed
core   +5 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The General Inner-Outer Factorization Problem for Discrete-Time Systems [PDF]

open access: yes, 1999
In this paper we give a theoretical and a computational solution to the most general inner-outer factorization problem formulated for a discrete-time system G.
A. Varga   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Discrete exterior geometry approach to structure-preserving discretization of distributed-parameter port-Hamiltonian systems [PDF]

open access: yes, 2011
This paper addresses the issue of structure-preserving discretization of open distributed-parameter systems with Hamiltonian dynamics. Employing the formalism of discrete exterior calculus, we introduce a simplicial Dirac structure as a discrete analogue
Seslija, Marko,   +11 more
core   +3 more sources

Evaluating a Method to Estimate Mediation Effects With Discrete-Time Survival Outcomes

open access: yesFrontiers in Psychology, 2019
The utility of evaluating mediation effects spans across research domains. The model facilitates investigation of underlying mechanisms of event timing and, as such, has the potential to help strengthen etiological research and inform intervention work ...
Amanda Jane Fairchild   +5 more
doaj   +1 more source

Model matching problem for discrete-time nonlinear systems; pp. 457–472 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2015
This paper addresses the model matching problem (MMP) for nonlinear single-input single-output discrete-time systems. The approach is based on the infinitesimal system description in terms of the one-forms that is converted into polynomial system ...
Juri Belikov   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

On a nonstationary discrete time infinite horizon growth model with uncertainty [PDF]

open access: yes, 1997
summary:In this paper we examine a nonstationary discrete time, infinite horizon growth model with uncertainty. Under very general hypotheses on the data of the model, we establish the existence of an optimal program and we show that the values of the ...
VERCILLO S.   +7 more
core   +1 more source

Discrete-time output feedback sliding-mode control design for uncertain systems using linear matrix inequalities [PDF]

open access: yes, 2011
An output feedback-based sliding-mode control design methodology for discrete-time systems is considered in this article. In previous work, it has been shown that by identifying a minimal set of current and past outputs, an augmented system can be ...
Floquet, Thierry   +7 more
core   +1 more source

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