Results 41 to 50 of about 23,280,557 (293)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Non-linear discrete-time observer design by sliding mode [PDF]
, 2007 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 09/02/2007.Research into observer design for non-linear discrete-time systems has produced many design methods.
Algarawi, Mohammed
core +6 more sources
Distinguishability of Discrete-Time Nonlinear Systems
IEEE Transactions on Automatic Control, 2014 This note considers the problem of identifying a discrete-time nonlinear system, within a finite family of possible models, from data sequences of a finite length. The problem is approached by resorting to the notion of output distinguishability. This amounts to asking whether output data sequences generated by different models can be distinguished ...
Marco Baglietto +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Convergence time towards periodic orbits in discrete dynamical systems. [PDF]
PLoS ONE, 2014 We investigate the convergence towards periodic orbits in discrete dynamical systems. We examine the probability that a randomly chosen point converges to a particular neighborhood of a periodic orbit in a fixed number of iterations, and we use ...
Jesús San Martín, Mason A Porter
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Discrete-Time Convergent Nonlinear Systems
IEEE Transactions on Automatic ControlzbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jungers, Marc +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Integrated fault estimation and accommodation design for discrete-time Takagi-Sugeno fuzzy systems with actuator faults [PDF]
, 2011 This paper addresses the problem of integrated robust fault estimation (FE) and accommodation for discrete-time Takagi–Sugeno (T–S) fuzzy systems. First, a multiconstrained reduced-order FE observer (RFEO) is proposed to achieve FE for discrete-time ...
Zhang, Ke +8 more
core +1 more source