Results 41 to 50 of about 198,239 (306)

Cost Accounting Algorithm of Environmental Pollution Control Based on Discrete Probability

open access: yesDiscrete Dynamics in Nature and Society, 2022
Aiming at the problems of high error rate and long time of traditional environmental pollution control cost accounting algorithm, a cost accounting algorithm of environmental pollution control based on discrete probability was designed. Firstly, the cost
Bing Xu
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Probability-dependent gain-scheduled control for discrete stochastic delayed systems with randomly occurring nonlinearities [PDF]

open access: yes, 2012
This is the post-print version of the Article. The official published version can be accessed from the links below - Copyright @ 2012 John Wiley & Sons, Ltd.In this paper, the gain-scheduled control problem is addressed by using probability-dependent ...
Wang, Z, Wei, G, Shen, B
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Optimal policies for discrete time risk processes with a Markov chain investment model [PDF]

open access: yes, 2006
We consider a discrete risk process modelled by a Markov Decision Process. The surplus could be invested in stock market assets. We adopt a realistic point of view and we let the investment return process to be statistically dependent over time.
Romera, Rosario, Diasparra, Maikol
core  

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

Introduction to Probability Theory [PDF]

open access: yes, 2012
In this course, the student will learn the basic terminology and concepts of probability theory, including sample size, random experiments, outcome spaces, discrete distribution, probability density function, expected values, and conditional probability.
The Saylor Foundation
core  

Modeling multi‐scale occupancy for monitoring rare and highly mobile species

open access: yesEcosphere, 2021
Occupancy‐based methods are commonly used to model the distribution, habitat use, and relative abundance of species. In particular, occupancy‐based methods are often recommended for monitoring species, allowing researchers to track population trends ...
Robert L. Emmet   +2 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

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