Results 61 to 70 of about 206,811 (263)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Validity of Erythrocyte Indices in Differentiation between Iron Deficiency Anemia and β-Thalassemia Trait in Children

The Journal of Pediatric Academy
Iron deficiency anemia (IDA) and β-thalassemia trait (BTT) are the most common causes of hypochromic microcytic anemia (HMA). Various erythrocyte indices that may help in the initial discrimination between IDA and BTT have been reported, but data ...
Emel Uzunoğlu, Ebru Yılmaz Keskin
doaj   +1 more source

Discriminative Indexing for Probabilistic Image Patch Priors [PDF]

, 2014
Newly emerged probabilistic image patch priors, such as Expected Patch Log-Likelihood (EPLL), have shown excellent performance on image restoration tasks, especially deconvolution, due to its rich expressiveness. However, its applicability is limited by the heavy computation involved in the associated optimization process.
Yan Wang, Sunghyun Cho, Jue Wang, Shih-Fu Chang   +3 more
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Evaluation of Discrimination Indices Validity for Screening of β-Thalassemia Trait [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives: β-thalassemia trait (β-TT) and iron deficiency anemia (IDA) are the most common forms of microcytic anemia. Screening of β-thalassemia trait is important for medical counseling before marriage and preventing β-thalassemia major
Ahmadi A., Mirzaee Khalilabadi R., Noorozi M., Cohan N., Ramzi M.   +4 more
doaj   +2 more sources

Düzce Üniversitesi Tıp Fakültesi Öğrencilerine Uygulanan Sınavlarda Soruların Geçerlik ve Güvenirlik Analizi

Düzce Tıp Fakültesi Dergisi, 2018
Amaç: Bu araştırmanın amacı Düzce Üniversitesi Tıp Fakültesi Dönem I, Dönem II ve Dönem III öğrencilerine uygulanan sınav sorularının geçerlik ve güvenirlik analizlerini yapmaktır.Gereç ve Yöntemler: Düzce Üniversitesi Tıp Fakültesi Öğrenci İşlerinden ...
Handan ANKARALI, Şengül CANGÜR, Mehmet Ali SUNGUR, Safinaz ATAOĞLU   +3 more
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Prediction Ability of Charlson, Elixhauser, and Rx-Risk Comorbidity Indices for Mortality in Patients with Hip Fracture. A Danish Population-Based Cohort Study from 2014 – 2018

Clinical Epidemiology, 2022
Jeppe Damgren Vesterager, Morten Madsen, Thomas Johannesson Hjelholt, Pia Kjær Kristensen, Alma Becic Pedersen Department of Clinical Epidemiology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Aarhus ...
Vesterager JD, Madsen M, Hjelholt TJ, Kristensen PK, Pedersen AB   +4 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source