Results 121 to 130 of about 1,967,846 (356)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Long-term results after liver transplantation for primary hepatic epithelioid hemangioendothelioma [PDF]

, 1995
Background: Hepatic epithelioid hemangioendothelioma (PHEHE) is a multifocal, low-grade malignant neoplasia characterized by its epithelial-like appearance and vascular endothelial histogenesis.
American Joint Committee on Cancer, B Koneru, D. D. Karavias, H. R. Doyle, I. R. Marino, J. J. Fung, J. R. Madariaga, JG O'Grady, JY Scoazec, KG Ishak, M. A. Nalesnik, MB Kelleher, MP Holley, PJ Dean, RD Gordon, S Iwatsuki, S. Iwatsuki, SW Weiss, SW Weiss, T Tereda, T. E. Starzl, TE Starzl   +21 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

P951: IMPACT OF MEASURABLE RESIDUAL DISEASE (MRD) DIFFERENCES ON PROGRESSION-FREE SURVIVAL (PFS): AN AGGREGATE DATA ANALYSIS FROM RANDOMIZED CLINICAL TRIALS IN MULTIPLE MYELOMA (MM)

, 2023
Bruno Paiva, Anastasiia Zherniakova, Jorge Núñez, Paula Rodríguez‐Otero, Qian Shi, Nikhil C. Munshi, Brian G.M. Durie, Jesús F. San Miguel   +7 more
openalex   +1 more source

Interferon free antiviral treatment of chronic hepatitis C in patients affected by β-thalassemia major [PDF]

, 2017
Chronic hepatitis C (CHC) significantly affects the prognosis of liver disease [1] and health related quality of life (HRQOL) in patients with β-thalassemia major [2, 3].
Biliotti, Elisa, Esvan, Rozenn, Franchi, Cristiana, Palazzo, Donatella, Serani, Marco, Silvestri, Alessandro M., Sorrentino, Francesco, Spaziante, Martina, Taliani, Gloria, Volpicelli, Lorenzo   +9 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Prognostic significance of programmed cell death 1 expression on CD8+T cells in various cancers: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundIncreased PD-1 expression on CD8+ T cells is considered as a hallmark for T-cell exhaustion, and is thought to be related to the prognosis of cancer patients.
Zhiyong Wan, Meng Cui, Jia Yang, Dan Liao, Junliang Chen, Fanmin Li, Yin Xiang, Zhiwei Cui, Yang Yang   +8 more
doaj   +1 more source

Comparative efficacy of 5flourouracil/calcium leucovorine versus 5flourouracil/calcium leucovorine plus oxaliplatin in the adjuvant treatment of colonic carcinoma in Kashmir

South Asian Journal of Cancer, 2013
Aim: This prospective, randomized comparative study conducted in Kashmir evaluated the clinical profile of colonic carcinoma and the efficacy, side effects and survival advantage of adjuvant treatment with 5FU/CLV versus FOLFOX7.
Hamid Deva Shaiq, Sheikh Aejaz Aziz, Imran R Rangreze, Omar J Shah, Shehla Shafi Khan   +4 more
doaj   +1 more source

Improved disease-free survival with adjuvant radiotherapy in early-stage endometrial cancer: 10-year outcome analysis [PDF]

, 2020
Suheyla Arslan, Gülhan Güler Avcı, Ebru Atasever Akkaş, Yıldız Güney   +3 more
openalex   +1 more source

Sequential immune-targeted surgical therapy resulted in disease-free survival in a case with advanced renal cell carcinoma [PDF]

, 2021
Kenichi Nishimura, Noriyoshi Miura, Naoya Sugihara, Keisuke Funaki, Kanae Koyama, Yuichiro Sawada, Terutaka Noda, Tetsuya Fukumoto, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika, Masafumi Matsumura, Katsuyoshi Hashine, Mashio Taniwaki   +13 more
openalex   +1 more source