Results 51 to 60 of about 1,967,846 (356)

High expression of metabolic enzyme PFKFB4 is associated with poor prognosis of operable breast cancer

Cancer Cell International, 2019
Background Enhanced glycolysis in tumors, known as the Warburg effect, provides the metabolic basis of enhanced cancer cell proliferation and metastasis.
Ling Yao, Lei Wang, Zhi-Gang Cao, Xin Hu, Zhi-Ming Shao   +4 more
doaj   +1 more source

Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM. [PDF]

, 2019
BackgroundThis pooled analysis investigated the prognostic value of depth of response in two cohorts of patients with BRAFV600-mutated metastatic melanoma treated with vemurafenib or cobimetinib plus vemurafenib.MethodsThe data were pooled from BRIM-2 ...
Ascierto, Paolo A, Dréno, Brigitte, Flaherty, Keith T, Hauschild, Axel, Larkin, James, Lewis, Karl D, McArthur, Grant A, McKenna, Edward, Mun, Yong, Ribas, Antoni, Wongchenko, Matthew, Yan, Yibing, Zhu, Qian   +12 more
core   +2 more sources

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

The clinicopathological characteristics of POLE-mutated/ultramutated endometrial carcinoma and prognostic value of POLE status: a meta-analysis based on 49 articles incorporating 12,120 patients

BMC Cancer, 2022
Objective This study was designed to investigate the frequency and clinicopathological characteristics of POLE-mutated/ultramutated (POLEmut) in endometrial carcinoma (EC) and assess the prognostic values of POLE status. Methods Electronic databases were
Qing Wu, Nianhai Zhang, Xianhe Xie
doaj   +1 more source

Relationship of Driver Oncogenes to Long-Term Pemetrexed Response in Non--Small-Cell Lung Cancer. [PDF]

, 2015
BackgroundPemetrexed is approved in the treatment of advanced stage nonsquamous non-small-cell lung cancer (NSCLC). The length of response is variable, and we thus sought to identify which clinicopathologic characteristics are associated with long-term ...
Liang, Ying, Neal, Joel W, Wakelee, Heather A   +2 more
core   +1 more source

Disease-free survival in patients with non-metastatic breast cancer [PDF]

Revista da Associação Médica Brasileira, 2016
SUMMARY Introduction: Breast cancer is the second most common malignancy in the world and the one with highest incidence in the female population; it is also a major cause of death from cancer among women. Objective: To analyze the disease-free survival (DFS) at 5 years and prognostic factors in women with non-metastatic invasive breast cancer treated ...
Diniz, Roberta Wolp, Guerra, Maximiliano Ribeiro, Cintra, Jane Rocha Duarte, Fayer, Vívian Assis, Teixeira, Maria Teresa Bustamante   +4 more
openaire   +4 more sources

A Systematic Review on Overall Survival and Disease-Free Survival Following Total Pelvic Exenteration

Asian Pacific Journal of Cancer Prevention, 2022
Total Pelvic Exenteration (TPE) is a radical operation for malignancies in which all of the organs inside the pelvic cavity, including the female reproductive organs, the lower urinary tract, and a part of the rectosigmoid are removed. In this study, we aimed to conduct a systematic review to assess the overall survival (OS) and disease-free survival ...
Miri, Seyed Rouhollah, Akhavan, Setareh, Mousavi, Azam Sadat, Hashemi, Seyedeh Razieh, Sheikhhasani, Shahrzad, Almasi-Hashiani, Amir, Fakhari, Mohammad Sadegh, Esmailzadeh, Arezoo   +7 more
openaire   +2 more sources

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Favorable Long-Term Outcome in Male Breast Cancer

European Journal of Breast Health, 2018
Objective: Male breast cancer (MBC) is a rare type of cancer in the breast cancer series and in the male population. Data is usually extrapolated from female breast cancer (FBC) studies. We aim to study the clinicopathological characteristics and outcome
Enver Özkurt, Mustafa Tükenmez, Ravza Yılmaz, Neslihan Cabioğlu, Mahmut Müslümanoğlu, Ahmet Said Dinççağ, Abdullah İğci, Vahit Özmen   +7 more
doaj   +1 more source

The Search for an Ideal Definitive Treatment of Sinonasal Squamous Cell Carcinoma With Orbit Invasion [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. Sinonasal squamous cell carcinoma (SqCC) often invades the orbit. The treatment approach for sinonasal cancer that has spread to the orbit varies across medical centers and depends on the extent of the invasion.
Seung Cheol Han, Jeon Seong, Sung-Woo Cho, Hyun-Jik Kim, Jeong-Whun Kim, Dong-Young Kim, Chae-Seo Rhee, Tae-Bin Won   +7 more
doaj   +1 more source