Results 121 to 130 of about 12,421,057 (398)

Perceptions about data-informed decisions: an assessment of information-use in high HIV-prevalence settings in South Africa

open access: yesBMC Health Services Research, 2017
Background Information-use is an integral component of a routine health information system and essential to influence policy-making, program actions and research.
Edward Nicol   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Our shared burden of diseases [PDF]

open access: yesCurrent Biology, 2014
At the end of the year that saw Ebola virus disease dominate the news, experts warn that other zoonoses also pose serious threats. To prepare for disease outbreaks and avoid global epidemics, health services and researchers may have to adopt a broader perspective, known as the 'One Health' paradigm, which links the health of people, domestic and wild ...
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Caring for Caregivers: Addressing Caregiver Burden in Newtown, Connecticut [PDF]

open access: yes, 2017
In 2015, thirty-four million Americans provided unpaid care to an adult 50 years or older. Due to an aging population and an increased number of individuals living with chronic disease, the niche that caregivers occupy in healthcare administration will ...
Wunrow, Zachary
core   +1 more source

Heavy Tau Burden with Subtle Amyloid β Accumulation in the Cerebral Cortex and Cerebellum in a Case of Familial Alzheimer’s Disease with APP Osaka Mutation [PDF]

open access: gold, 2020
Hiroyuki Shimada   +12 more
openalex   +1 more source

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019

open access: yesLancet Public Health, 2022
Emma Jaimie D Stein Emil Kai Julian Foad Amir Ahmed Ema Nichols Steinmetz Vollset Fukutaki Chalek Abd-Alla   +264 more
semanticscholar   +1 more source

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