Results 91 to 100 of about 141,910 (306)

Reply to: Rethinking disease eradication: putting countries first. [PDF]

open access: yesInt Health, 2021
Hopkins DR   +4 more
europepmc   +1 more source

Pellagra: A Non-Eradicated Old Disease

open access: yesClinics and Practice, 2014
We report a case of a 50-year old homeless male who presented with pellagra and pellagrous encephalopathy. The characteristic - if not pathognomonic - skin lesions of pellagra support its diagnosis on solely clinical grounds. Clinicians should keep a high index of suspicion, in certain patient groups, in order to early diagnose and cure this ...
openaire   +3 more sources

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

open access: yesAdvanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin   +9 more
wiley   +1 more source

Polio eradication strategy 2022\u20132026 : delivering on a promise [PDF]

open access: yes
Over the last decade, the Global Polio Eradication Initiative (GPEI) made steady progress on the path to eradication. Wild poliovirus types 2 and 3 (WPV2 and WPV3) were declared eradicated in 2015 and 2019, respectively; the World Health Organization ...

core  

Helicobacter pylori and the management of gastro-oesophageal reflux disease [PDF]

open access: yes, 2005
This thesis is centred on the current controversy and possible links between H. pylori and GORD and whether the infection should be eradicated in those requiring long PPIs.
Raghunath, Anathakrishnapuram Srinivasan
core  

Genetic Code Expanded T Cell for Controllable Immunotherapy

open access: yesAdvanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang   +4 more
wiley   +1 more source

Farmer and Consumer Responses to African Swine Fever Outbreaks: Implications for Post-Outbreak Control and Eradication

open access: yesVeterinary Sciences
African swine fever (ASF) remains a major challenge for global animal disease prevention and control. Public sentiment during ASF, along with farmer and consumer behavior, are underexplored factors in ASF control. This study examines how public sentiment
Chi Ma, Wenfei Zhang
doaj   +1 more source

Global Polio Eradication progress 2001

open access: yes
The global incidence of polio fell to 483 new cases in 2001, bringing the disease to the brink of eradication. Wild poliovirus circulation is limited to parts of ten countries as the geographic spread and biodiversity of the virus has dramatically ...

core  

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

open access: yesAdvanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang   +9 more
wiley   +1 more source

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