Results 1 to 10 of about 1,894,026 (247)

The Effect of Bergenin on Isonicotinic Acid Hydrazide and Rifampicin-Induced Liver Injury Revealed by RNA Sequencing

open access: yesMolecules, 2023
Bergenin (BER), a natural component of polyphenols, has a variety of pharmacological activities, especially in improving drug metabolism, reducing cholestasis, anti-oxidative stress and inhibiting inflammatory responses.
Ting Li   +9 more
doaj   +1 more source

Effects of scoparone on non-alcoholic fatty liver disease revealed by RNA sequencing

open access: yesFrontiers in Endocrinology, 2022
Scoparone (SCO) is known to have curative effect of alleviating liver injury. The purpose of this study was to observe the therapeutic effect and possible mechanism of SCO against high-fat diet (HFD) induced non-alcoholic liver disease (NAFLD) through in
Xiaoyan Huang   +13 more
doaj   +1 more source

CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma

open access: yesCancer Cell International, 2021
Background Calmodulin1 (CALM1) has been identified as one of the overexpression genes in a variety of cancers and EGFR inhibitor have been widely used in clinical treatment but it is unknown whether CALM1 and epidermal growth factor receptor (EGFR) have ...
Tao Liu   +7 more
doaj   +1 more source

Development and validation of nomogram for unplanned ICU admission in patients with dilated cardiomyopathy

open access: yesFrontiers in Cardiovascular Medicine, 2023
ObjectiveUnplanned admission to the intensive care unit (ICU) is the major in-hospital adverse event for patients with dilated cardiomyopathy (DCM). We aimed to establish a nomogram of individualized risk prediction for unplanned ICU admission in DCM ...
Xiao-Lei Li   +20 more
doaj   +1 more source

Genetic Variation of Migration Inhibitory Factor Gene rs2070766 Is Associated With Acute Coronary Syndromes in Chinese Population

open access: yesFrontiers in Genetics, 2022
Genetic variation of macrophage migration inhibitory factor (MIF) gene has been linked to coronary artery disease. We investigated an association between the polymorphism of MIF gene rs2070766 and acute coronary syndromes (ACS) and the predictive value ...
Jin-Yu Zhang   +19 more
doaj   +1 more source

Cancer incidence in Behçet’s disease

open access: yesIrish Journal of Medical Science (1971 -), 2020
e13583 Background: Previous studies demonstrated increased risk of cancer in systemic autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE) and sjögren syndrome due to uncontrolled inflammation. Behçet’s disease (BD) was also reported to be associated with an increased risk of cancer, although data is limited and ...
Deniz Can Guven   +8 more
openaire   +3 more sources

Improving Fusarium Basal Rot Resistance of Onion Cultivars through Artificial Inoculation and Selection of Mature Bulbs

open access: yesHorticulturae, 2021
Fusarium basal rot (FBR) of onion, caused by the soil-borne fungus Fusarium oxysporum f.sp. cepae (FOC), results in a substantial storage loss of marketable bulbs.
Subhankar Mandal, Christopher S. Cramer
doaj   +1 more source

Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine

open access: yesBMC Genomics, 2021
Background Cystic echinococcosis (CE) is a life-threatening zoonosis caused by the larval form of Echinococcus granulosus tapeworm. Our previous study showed that an approved drug pyronaridine (PND) is highly effective against CE, both in vitro and in an
Yingfang Yu   +11 more
doaj   +1 more source

Association between MIF gene promoter rs755622 and susceptibility to coronary artery disease and inflammatory cytokines in the Chinese Han population

open access: yesScientific Reports, 2021
Macrophage migration inhibitory factor (MIF) is an essential mediator of atherosclerotic plaque progression and instability leading to intracoronary thrombosis, therefore contributing to coronary artery disease (CAD).
Jun-Yi Luo   +8 more
doaj   +1 more source

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