Results 51 to 60 of about 3,366,354 (282)

Blocking NKG2A in Echinococcus multilocularis infection partially relieves impairment of NK cell function of the host

open access: yesCellular and Molecular Life Sciences
Background Alveolar echinococcosis (AE) is a fatal zoonotic parasitic disease with biological characteristics similar to cancer. Although previous studies have reported immune dysfunction of Natural Killer (NK) cells due to other inhibitory receptors in ...
Ayinuer Aierken   +8 more
doaj   +1 more source

Phenotype and function of MAIT cells in patients with alveolar echinococcosis

open access: yesFrontiers in Immunology
Mucosal-associated invariant T (MAIT) cells are a subpopulation of unconventional T cells widely involved in chronic liver diseases. However, the potential role and regulating factors of MAIT cells in alveolar echinococcosis (AE), a zoonotic parasitic ...
Jintian Li   +11 more
doaj   +1 more source

Association between MIF gene promoter rs755622 and susceptibility to coronary artery disease and inflammatory cytokines in the Chinese Han population

open access: yesScientific Reports, 2021
Macrophage migration inhibitory factor (MIF) is an essential mediator of atherosclerotic plaque progression and instability leading to intracoronary thrombosis, therefore contributing to coronary artery disease (CAD).
Jun-Yi Luo   +8 more
doaj   +1 more source

Global Stability of an SIR Epidemic Model with Delay and General Nonlinear Incidence [PDF]

open access: yes, 2010
An SIR model with distributed delay and a general incidence function is studied. Conditions are given under which the system exhibits threshold behaviour: the disease-free equilibrium is globally asymptotically stable if R0 \u3c 1 and globally attracting
McCluskey, C. Connell
core   +2 more sources

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter   +17 more
wiley   +1 more source

The association between Clonorchis sinensis seropositivity and hepatocellular carcinoma in an endemic area: a study in Guangxi, China

open access: yesBMC Infectious Diseases
Background Chronic infection with Clonorchis sinensis (C.sinensis) has been associated swith the development of intrahepatic cholangiocarcinoma (ICC); however, the relationship between C.sinensis and hepatocellular carcinoma (HCC) remains uncertain ...
Qing-Li Yang   +9 more
doaj   +1 more source

Epidemiological features of COVID-19 in Iran

open access: yesJournal of Research in Medical Sciences, 2022
Background: The first confirmed case of COVID-19 in Iran was reported in February 2019. The current study aimed to investigate the epidemiological aspects of COVID-19 disease in Isfahan province and evaluate the chances of infection and death in the ...
Negah Tavakolifard   +5 more
doaj   +1 more source

Mathematical Model of Vaccine Noncompliance [PDF]

open access: yes, 2016
Vaccine scares can prevent individuals from complying with a vaccination program. When compliance is high, the critical vaccination proportion is close to being met, and herd immunity occurs, bringing the disease incidence to extremely low levels.
Bauer, Jordan, Capaldi, Alex
core   +2 more sources

Obesity and kidney stone disease. A systematic review [PDF]

open access: yes, 2018
INTRODUCTION: Currently, abdominal obesity has reached an epidemic stage and obesity represents an important challenge for worldwide health authorities. Epidemiologic studies have demonstrated that the stone risk incidence increases with Body Mass Index,
AL SALHI, Yazan   +8 more
core   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

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