Results 231 to 240 of about 1,230,509 (271)

Advanced predictive disease modeling in biomedical IoT using the temporal adaptive neural evolutionary algorithm. [PDF]

Sci Rep
S C, C A, K S.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Translational disease modeling of peripheral blood identifies type 2 diabetes biomarkers predictive of Alzheimer's disease. [PDF]

NPJ Syst Biol Appl
Ball BK, Park JH, Bergendorf AM, Proctor EA, Brubaker DK.   +4 more
europepmc   +1 more source

Induced Pluripotent (iPSC) and Mesenchymal (MSC) Stem Cells for In Vitro Disease Modeling and Regenerative Medicine. [PDF]

Int J Mol Sci
Panferov E, Dodina M, Reshetnikov V, Ryapolova A, Ivanov R, Karabelsky A, Minskaia E.   +6 more
europepmc   +1 more source

Organoids in biomedicine: Bridging innovation, disease modeling, and regulatory transformation. [PDF]

Cell Transplant
Cai C, Han X.
europepmc   +1 more source

Induced Pluripotent Stem Cells in Cardiomyopathy: Advancing Disease Modeling, Therapeutic Development, and Regenerative Therapy. [PDF]

Int J Mol Sci
Vo QD, Nakamura K, Saito Y, Akagi S, Miyoshi T, Yuasa S.   +5 more
europepmc   +1 more source

Organ-on-a-Chip Models-New Possibilities in Experimental Science and Disease Modeling. [PDF]

Biomolecules
Wysoczański B, Świątek M, Wójcik-Gładysz A.   +2 more
europepmc   +1 more source

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Disease model: Parkinson's disease

Trends in Molecular Medicine, 2003
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is primarily characterized by the degeneration of dopaminergic neurons in the nigrostriatal pathway. The pathology of PD is typified by the presence of cytoplasmic inclusions (Lewy bodies) containing alpha-synuclein and ubiquitin.
Shun, Shimohama, Hideyuki, Sawada, Yoshihisa, Kitamura, Takashi, Taniguchi   +3 more
openaire   +2 more sources

Disease Modeling

2022
Mathematical models are essential components of the toolbox of any disease ecologist. They should be used as an integral part of any investigation into the impact and management of infectious disease in wildlife populations. Simple models are important to conceptualize the processes occurring during host–pathogen interactions and to identify key ...
Johannes Foufopoulos, Gary A. Wobeser, Hamish McCallum   +2 more
openaire   +1 more source