Results 111 to 120 of about 659,696 (286)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Mathematical Modeling for Inherited Diseases
Computational and Mathematical Methods in Medicine, 2017 We introduced a new nonassociative algebra, namely, left almost algebra, and discussed some of its genetic properties. We discussed the relation of this algebra with flexible algebra, Jordan algebra, and generalized Jordan algebra.
Saima Anis, Madad Khan, Saqib Khan
openaire +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
BMC Infectious Diseases, 2018 Background The effects of maternal influenza infection on the fetus remain unclear. We studied mild influenza and influenza antibodies in relation to birth weight and risks of pre-eclampsia, preterm birth (PTB), and small for gestational age (SGA) birth ...
Ida Laake +7 more
doaj +1 more source
The Primary Sectors of the Economy and the Dutch Disease in Nigeria [PDF]
This study examines whether the Dutch Disease—a resource boom leading to the decline of the erstwhile tradable sector—is present in Nigeria in the light of the rejection of the Dutch Disease thesis in other studies on Nigeria.
J. O. Olusi, M. A. Olagunju
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Estimates of epidemiological parameters for H5N1 influenza in humans: a rapid review
BMC Infectious DiseasesBackground The ongoing H5N1 panzootic in mammals has amplified zoonotic pathways to facilitate human infection. Characterising key epidemiological parameters for H5N1 is critical should it become widespread.
Jack Ward +9 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source