Results 61 to 70 of about 16,121,002 (311)
Evidence for Conversion of Methanol to Formaldehyde in Nonhuman Primate Brain
Analytical Cellular Pathology, 2016 Many studies have reported that methanol toxicity to primates is mainly associated with its metabolites, formaldehyde (FA) and formic acid. While methanol metabolism and toxicology have been best studied in peripheral organs, little study has focused on ...
Rongwei Zhai +3 more
doaj +1 more source
Animal Models and Experimental Medicine, 2023 Background New Omicron subvariants are emerging rapidly from BA.1 to BA.4 and BA.5. Their pathogenicity has changed from that of wild‐type (WH‐09) and Omicron variants have over time become globally dominant.
Yaqing Zhang +8 more
doaj +1 more source
Animal Models of Alzheimer Disease [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Significant insights into the function of genes associated with Alzheimer disease and related dementias have occurred through studying genetically modified animals. Although none of the existing models fully reproduces the complete spectrum of this insidious human disease, critical aspects of Alzheimer pathology and disease processes can be ...
LaFerla, Frank M, Green, Kim N
openaire +4 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
Animal models of soft-tissue sarcoma.
, 2010 Soft-tissue sarcomas (STSs) are rare mesenchymal tumors that arise from muscle, fat and connective tissue. Currently, over 75 subtypes of STS are recognized.
Kirsch, David G +5 more
core +1 more source
Molecular NeurodegenerationBackground Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid-β plaques, tau hyperphosphorylation, and neuroinflammation.
Zhong-Jiang Yan +4 more
doaj +1 more source
Animal Models in Behçet's Disease [PDF]
Pathology Research International, 2012 Behçet's disease is a chronic, recurrent, multisystemic, inflammatory disorder affecting mainly the oral and urogenital mucosa and the uveal tract. Although the etiology and pathogenesis of Behçet's disease are unknown, numerous etiologies have been proposed, including environmental, infectious, and immunological factors; an autoimmune basis ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Editorial: Unconventional Animal Models in Infectious Disease Research – Part I [PDF]
, 2021 Editorial on the Research Topic Unconventional Animal Models in Infectious Disease ...
Younes, Nadin +3 more
core +1 more source