Results 61 to 70 of about 1,196,955 (314)
Cell Reports, 2016 Here, we examine whether neurons differentiated from transplanted stem cells can integrate into the host neural network and function in awake animals, a goal of transplanted stem cell therapy in the brain.
Jing-kuan Wei +23 more
doaj +1 more source
Animal Models and Experimental Medicine, 2023 Background New Omicron subvariants are emerging rapidly from BA.1 to BA.4 and BA.5. Their pathogenicity has changed from that of wild‐type (WH‐09) and Omicron variants have over time become globally dominant.
Yaqing Zhang +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
Animal models of autoimmune diseases [PDF]
Rheumatology International, 1997 Failure of distinction between self and non-self is regarded a critical event in the pathogenesis of several human diseases such as systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, uveoretinitis or diabetes mellitus.
Burkhardt, H., Kalden, J. R.
openaire +2 more sources
Translational challenges of animal models in Chagas disease drug development: a review [PDF]
, 2015 Eric Chatelain,1 Nandini Konar21Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland; 2Merck & Co, Inc, Whitehouse Station, NJ, USAAbstract: Chagas disease, or American trypanosomiasis, caused by Trypanosoma cruzi parasite infection is
Konar N, Chatelain E
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Functional genomics reveal gene regulatory mechanisms underlying schizophrenia risk
Nature Communications, 2019 We know a large number of risk SNPs for schizophrenia, but little about how these SNPs contribute to the disorder. Here, the authors use functional genomics to identify risk SNPs that disrupt transcription factor binding and validate the regulatory ...
Yongxia Huo +4 more
doaj +1 more source
Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel
Toxins, 2015 The intense pain induced by scorpion sting is a frequent clinical manifestation. To date, there is no established protocol with significant efficacy to alleviate the pain induced by scorpion envenomation.
Md Abdul Hakim +6 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Evidence for Conversion of Methanol to Formaldehyde in Nonhuman Primate Brain
Analytical Cellular Pathology, 2016 Many studies have reported that methanol toxicity to primates is mainly associated with its metabolites, formaldehyde (FA) and formic acid. While methanol metabolism and toxicology have been best studied in peripheral organs, little study has focused on ...
Rongwei Zhai +3 more
doaj +1 more source