Results 41 to 50 of about 16,121,002 (311)
ResearchThe ANK2 gene mutations are marked risk factors for autism spectrum disorder, one of the neurodevelopmental disorders (NDDs) that often extends into adulthood and has a complex etiology involving genetic and environmental factors.
Hong-Di Huang +23 more
doaj +1 more source
Animal Models of Traumatic Brain Injury
, 2016 Animal models of traumatic brain injury (TBI) have been the core of the research on the molecular, cellular, and functional effects of the disease. To be able to simulate the heterogeneous aspects of TBI several models have been designed.
Fredrik Clausen, Clausen, Fredrik,
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
Animal models of disease: useful or not? [PDF]
, 2021 Faustino-Rocha AI. 2021. Animal models of disease: useful or not? From in silico to animal models for the study of human diseases.
Faustino-Rocha, Ana Isabel
core
Object-translocation induces event coding in the rat hippocampus
Communications BiologyEpisodic memory is the ability to recall personally experienced events that are situated within specific spatial contexts. Within a navigation environment, salient objects can function as landmarks, and interactions with them can be encoded as distinct ...
Ya-Li Duan +9 more
doaj +1 more source
Bidirectional genetic overlap between bipolar disorder and intelligence
BMC Medicine, 2022 Background Bipolar disorder (BD) is a highly heritable psychiatric illness exhibiting substantial correlation with intelligence. Methods To investigate the shared genetic signatures between BD and intelligence, we utilized the summary statistics from ...
Meng-Yuan Shang +8 more
doaj +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Molecular Cancer, 2021 Background Non-small cell lung cancer (NSCLC) is the most common type of human lung cancers, which has diverse pathological features. Although many signaling pathways and therapeutic targets have been defined to play important roles in NSCLC, limiting ...
Yaomei He +10 more
doaj +1 more source
Animal Models of Airway Diseases [PDF]
, 2011 Over the past 20 years, the growing awareness that purinergic signaling events literally shape the immune and inflammatory responses to infection and allergic reactions warranted the development of animal models to assess their importance in vivo in acute lung injury and chronic airway diseases.
Thompson, Linda F. +2 more
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source