Results 31 to 40 of about 1,930,568 (317)

Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM. [PDF]

open access: yes, 2017
Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of feline HCM make it an ...
Freeman, Lisa M   +4 more
core   +2 more sources

Animal Models for Periodontal Disease [PDF]

open access: yesBioMed Research International, 2011
Animal models and cell cultures have contributed new knowledge in biological sciences, including periodontology. Although cultured cells can be used to study physiological processes that occur during the pathogenesis of periodontitis, the complex host response fundamentally responsible for this disease cannot be reproduced in vitro.
Oz, Helieh S., Puleo, David A.
openaire   +2 more sources

Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

open access: yesScientific Reports, 2017
The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging.
Hong-Yi Zheng   +11 more
doaj   +1 more source

Isolation of Joint-infiltrating Cells

open access: yesBio-Protocol, 2016
Infiltration of leukocytes into joints is one of the main features of autoimmune inflammatory arthritis. Here, we describe the protocol for isolation of joint-infiltrating cells in mice.
Aoi Akitsu, Yoichiro Iwakura
doaj   +1 more source

Cohesin promotes HSV-1 lytic transcription by facilitating the binding of RNA Pol II on viral genes

open access: yesVirology Journal, 2021
Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus.
Xin Li   +10 more
doaj   +1 more source

SyntenyVista [PDF]

open access: yes, 2004
Visualization of genome comparisons is an important research tool in biology, medicine and agricultural research. We present a new visualization system, SyntenyVista, which allows for interactive exploration of genome comparisons. It incorporates a novel
Hanlon, N., Hunt, E.
core   +1 more source

Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function

open access: yesBMC Medicine, 2023
Background Schizophrenia and bipolar disorder (BD) are believed to share clinical symptoms, genetic risk, etiological factors, and pathogenic mechanisms.
Zhi-Hui Yang   +13 more
doaj   +1 more source

Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]

open access: yes, 2014
In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core   +1 more source

Vaccination is a suitable tool in the control of Aujeszky's disease outbreaks in pigs using a Population Dynamics P systems model [PDF]

open access: yes, 2020
Aujeszky's disease is one of the main pig viral diseases and results in considerable economic losses in the pork production industry. The disease can be controlled using preventive measures such as improved stock management and vaccination throughout the
Colomer, M. Àngels (Maria Àngels)   +2 more
core   +3 more sources

Animal models of autoimmune diseases [PDF]

open access: yesRheumatology International, 1997
Failure of distinction between self and non-self is regarded a critical event in the pathogenesis of several human diseases such as systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, uveoretinitis or diabetes mellitus.
Burkhardt, H., Kalden, J. R.
openaire   +2 more sources

Home - About - Disclaimer - Privacy