Results 181 to 190 of about 7,373,821 (305)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Common MC1R Variants and Parkinson Disease Progression.

JAMA Neurol
Schumacher JG, Zhang X, Wang J, Dijkstra JM, Watanabe H, Gao X, Cortese M, Macklin EA, Schwarzschild MA, Chen X.   +9 more
europepmc   +1 more source

Extracellular Vesicles as Mediators of Pathophysiology and Disease Progression in Cardiovascular Diseases. [PDF]

Int J Mol Sci
Tangos M, Schneider L, Jarkas O, El-Battrawy I, Hamdani N.   +4 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Time-Updated Hematuria and Kidney Disease Progression in IgAN. [PDF]

Kidney Int Rep
Tang C, Si FL, Chen P, Hou WY, Yang HY, Lv JC, Shi SF, Zhou XJ, Liu LJ, Zhang H.   +9 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

To Progress or Not to Progress, That Is the Question! Progression in Fibrotic Interstitial Lung Disease

American Journal of Respiratory and Critical Care Medicine, 2023
openaire   +2 more sources

Editorial: Precision medicine in viral hepatitis: progress and prospects towards elimination

Frontiers in Cellular and Infection Microbiology
Amanda Fernández-Rodríguez, Amanda Fernández-Rodríguez, Pamela Valva   +2 more
doaj   +1 more source

Comorbidities in multiple sclerosis: acquired hepatocerebral degeneration mimicking disease progression. [PDF]

Neurol Sci
Einsiedler M, Polymeris A, Raptis N, Beyer A, Becker D, Krassenburg L, Panne I, Mahmutoglu MA, Lieb JM, Rüegg S, Derfuss T, Kuhle J.   +11 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source