Results 191 to 200 of about 13,239,682 (316)
Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer +11 morewiley +1 more sourceIdentification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Lancet Neurology, 2017 D. H. Moss, A. Pardiñas, D. Langbehn, K. Lo, B. Leavitt, R. Roos, A. Durr, S. Mead, P. Holmans, L. Jones, S. Tabrizi, A. Coleman, R. Santos, J. Decolongon, A. Sturrock, É. Bardinet, C. J. Ret, D. Justo, S. Lehéricy, C. Marelli, K. Nigaud, R. Valabrègue, S. Bogaard, E. Dumas, J. Grond, E. t'Hart, C. Jurgens, M. Witjes-Ané, N. Arran, J. Callaghan, C. Stopford, C. Frost, R. Jones, N. Hobbs, N. Lahiri, R. Ordidge, G. Owen, T. Pepple, J. Read, M. Say, E. Wild, A. Patel, N. Fox, C. Gibbard, I. Malone, H. Crawford, D. Whitehead, S. Keenan, D. Cash, C. Berna, N. Bechtel, S. Bohlen, A. Man, P. Kraus, E. Axelson, C. Wang, T. Acharya, S. Lee, W. Monaco, C. Campbell, S. Queller, K. Whitlock, M. Campbell, E. Frajman, C. Milchman, A. O'Regan, I. Labuschagne, J. Stout, B. Landwehrmeyer, D. Craufurd, R. Scahill, S. Hicks, C. Kennard, H. Johnson, A. Tobin, H. Rosas, R. Reilmann, B. Borowsky, C. Pourchot, S. Andrews, A. Bachoud-Lévi, A. Bentivoglio, I. Biunno, R. Bonelli, J. Burgunder, Stephen C. Dunnett, J. Ferreira, O. Handley, A. Heiberg, T. Illmann, G. Landwehrmeyer, Jamie Levey, M. Ramos-Arroyo, J. Nielsen, Susana Pro Koivisto, M. Päivärinta, R. Roos, A. Sebastián, S. Tabrizi, W. Vandenberghe, C. Verellen‐Dumoulin, T. Uhrová, J. Wahlström, J. Zaremba, V. Baake, K. Barth, M. B. Garde, Sabrina Betz, R. Bos, J. Callaghan, A. Come, L. Guedes, D. Ecker, Ana Maria Finisterra, R. Fullam, M. Gilling, L. Gustafsson, O. Handley, C. Hvalstedt, C. Held, Kerstin Koppers, C. Lamanna, M. Laurá, Asunción Martínez Descals, S. Martínez-Horta, T. Mestre, S. Minster, D. Monza, Lisanne Mütze, Martin Oehmen, M. Orth, H. Padieu, Laurent Paterski, N. Peppa, M. D. Renzo, A. Rialland, Niini Røren, P. Šašinková, Erika Timewell, J. Townhill, P. Cubillo, Wildson Vieira da Silva, M. V. Walsem, Carina Whalstedt, M. Witjes-Ané, G. Witkowski, Abigail L. Wright, D. Zielonka, E. Zielonka, P. Zinzi, R. Bonelli, S. Lilek, K. Hecht, Brigitte Herranhof, A. Holl, H. Kapfhammer, M. Koppitz, M. Magnet, N. Müller, Daniela Otti, A. Painold, Karin Reisinger, Monika Scheibl, H. Schöggl, J. Ullah, E. Braunwarth, F. Brugger, Lisa Buratti, E. Hametner, C. Hepperger, Christiane Holas, A. Hotter, A. Hussl, C. Müller, W. Poewe, K. Seppi, F. Sprenger, G. Wenning, A. Boogaerts, Godelinde Calmeyn, I. Delvaux, Dirk Liessens, N. Somers, Michel Dupuit, C. Minet, Dominique van Paemel, P. Ribaï, Dimphna van Reijen, J. Klempír, V. Majerova, J. Roth, I. Stárková, L. Hjermind, O. Jacobsen, J. Nielsen, I. U. Larsen, Tua Vinther-Jensen, Heli Hiivola, H. Hyppönen, K. Martikainen, Katri Tuuha, P. Allain, D. Bonneau, M. Bost, B. Gohier, Marie-Anne Guérid, Audrey Olivier, Adriana Prundean, C. Scherer-Gagou, C. Verny, Blandine Babiloni, S. Debruxelles, Charlotte Duché, C. Goizet, Laetitia Jameau, Danielle Lafoucrière, U. Spampinato, Rekha Barthélémy, Chris De Bruycker, Maryline Cabaret Anne-Sophie Carette, Éric Defebvre, M. Delliaux, A. Delval, A. Destée, K. Dujardin, Marie-Hélène Lemaire, S. Manouvrier, M. Peter, Lucie Plomhouse, B. Sablonnière, C. Simonin, Stéphanie Thibault-Tanchou, I. Vuillaume, Marcellin Bellonet, H. Berrissoul, S. Blin, F. Courtin, C. Duru, Véronique Fasquel, O. Godefroy, P. Krystkowiak, Béatrice Mantaux, M. Roussel, Sandrine Wannepain, J. Azulay, Marie Delfini, A. Eusebio, F. Fluchère, Laura Mundler, M. Anheim, Céline Julie, Ouhaid Lagha Boukbiza, N. Longato, G. Rudolf, C. Tranchant, Marie-Agathe Zimmermann, C. Kosinski, E. Milkereit, D. Probst, K. Reetz, C. Saß, J. Schiefer, C. Schlangen, C. Werner, H. Gelderblom, J. Priller, H. Prüss, E. Spruth, G. Ellrichmann, Lennard Herrmann, R. Hoffmann, Barbara Kaminski, P. Kotz, C. Prehn, C. Saft, H. Lange, R. Maiwald, M. Löhle, A. Maass, S. Schmidt, Cecile Bosredon, A. Storch, Annett Wolz, M. Wolz, P. Capetian, J. Lambeck, B. Zucker, K. Boelmans, C. Ganos, Walburgis Heinicke, U. Hidding, J. Lewerenz, A. Münchau, Jenny Schmalfeld, Lars Stubbe, S. Zittel, G. Diercks, D. Dressler, Heike Gorzolla, C. Schrader, P. Tacik, Michael Ribbat, B. Longinus, K. Bürk, J. C. Möller, I. Rissling, M. Mühlau, A. Peinemann, M. Städtler, A. Weindl, J. Winkelmann, C. Ziegler, N. Bechtel, H. Beckmann, S. Bohlen, E. Hölzner, R. Reilmann, S. Rohm, S. Rumpf, S. Schepers, N. Weber, M. Dose, Gabriele Leythäuser, R. Marquard, T. Raab, A. Wiedemann, A. Buck, Julia Connemann, C. Geitner, Andrea Kesse, B. Landwehrmeyer, Christina Lang, F. Lezius, S. Nepper, A. Nieß, A. Schneider, D. Schwenk, S. Süssmuth, S. Trautmann, P. Weydt, C. Cormio, V. Sciruicchio, C. Serpino, M. Tommaso, S. Capellari, P. Cortelli, Roberto Galassi, G. Rizzo, R. Poda, C. Scaglione, E. Bertini, E. Ghelli, A. Ginestroni, F. Massaro, C. Mechi, M. Paganini, S. Piacentini, S. Pradella, A. Romoli, S. Sorbi, G. Abbruzzese, M. B. D. Poggio, G. Ferrandes, P. Mandich, R. Marchese, A. Albanese, D. Bella, A. Castaldo, S. Donato, C. Gellera, S. Genitrini, C. Mariotti, L. Nanetti, D. Paridi, P. Soliveri, C. Tomasello, G. Michele, L. Maio, M. Massarelli, S. Peluso, A. Roca, C. Russo, E. Salvatore, P. Sorrentino, E. Amico, Mariagrazia Favellato, A. Griguoli, Irene Mazzante, Martina Petrollini, F. Squitieri, B. D’Alessio, Chiara Esposito, R. Bentivoglio, M. Frontali, A. Guidubaldi, T. Ialongo, G. Jacopini, C. Piano, S. Romano, F. Soleti, M. Spadaro, M. S. V. Hout, M. Verhoeven, J. V. Vugt, A. D. Weert, J.J.W. Bolwijn, M. Dekker, B. Kremer, K. Leenders, J. Oostrom, Simon J. A. van den Bogaard, E. Dumas, Elizabeth P. Hart, B. Kremer, C. Verstappen, O. Aaserud, C. JanFrich, R. Wehus, K. Bjørgo, M. Fannemel, Per F. Gørvell, E. Lorentzen, L. Retterstøl, Bodil Stokke, Inga Bjørnevoll, S. Sando, A. Dziadkiewicz, Małgorzata Nowak, P. Robowski, E. Sitek, J. Sławek, W. Sołtan, Michal Szinwelski, M. Blaszcyk, M. Boczarska-Jedynak, E. Ciach-Wysocka, A. Gorzkowska, B. Jasińska‐Myga, G. Kłodowska-Duda, G. Opala, D. Stompel, K. Banaszkiewicz, Dorota Bocwinska, Kamila Bojakowska-Jaremek, Małgorzata Dec, M. Krawczyk, M. Rudzińska, E. Szczygieł, A. Szczudlik, A. Wasielewska, M. Wójcik, A. Bryl, A. Ciesielska, A. Klimberg, J. Marcinkowski, H. Samara, J. Sempołowicz, Anna Gogol, P. Janik, H. Kwiecinski, Z. Jamrozik, J. Antczak, K. Jachińska, W. Krysa, M. Rakowicz, P. Richter, R. Rola, D. Ryglewicz, H. Sienkiewicz-Jarosz, I. Stępniak, A. Sułek, E. Zdzienicka, Karolina Zieora-Jakutowicz, J. Ferreira, M. Coelho, T. Mendes, A. Valadas, C. Andrade, Miguel Gago, C. Garrett, Maria Rosália Guerra, Carmen Durán Herrera, P. Garcia, M. A. Barberá, D. Guia, L. C. Hernanz, Judit López Catena, Pilar Quiléz Ferrer, A. Sebastián, Gemma Tome Carruesco, Jordi Bas, N. Busquets, M. Calopa, M. F. Robert, Celia Mareca Viladrich, Jesús Miguel Ruiz Idiago, Antonio Villa Riballo, E. Cubo, C. G. Polo, N. Mariscal +499 moresemanticscholar +1 more sourcePharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller +16 morewiley +1 more sourceRecognising disease progression in MGUS and smouldering myeloma: Biomarkers, symptom monitoring and imaging. [PDF]
Br J HaematolHaslam A, Iqbal G, Drayson M, Pratt G, Yong K, Dunn J, Atkin C, Bunce C, Howe D, Bowcock S. +9 moreeuropepmc +1 more sourceRaman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans +3 morewiley +1 more source