Results 31 to 40 of about 3,016,766 (291)

Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives

Patient Preference and Adherence, 2021
Elisabeth G Celius,1 Heidi Thompson,2 Maija Pontaga,3 Dawn Langdon,4 Alice Laroni,5 Stanca Potra,6 Trishna Bharadia,7 David Yeandle,8 Jane Shanahan,9 Pieter van Galen,10 Nektaria Alexandri,11 Jürg Kesselring12 1Deparment of Neurology, Oslo ...
Celius EG, Thompson H, Pontaga M, Langdon D, Laroni A, Potra S, Bharadia T, Yeandle D, Shanahan J, van Galen P, Alexandri N, Kesselring J   +11 more
doaj  

Predictors for Therapy Response to Intrathecal Corticosteroid Therapy in Multiple Sclerosis

Frontiers in Neurology, 2019
Objective: The autoimmune disease Multiple Sclerosis (MS) represents a heterogeneous disease pattern with an individual course that may lead to permanent disability.
Katja Vohl, Alexander Duscha, Barbara Gisevius, Johannes Kaisler, Ralf Gold, Aiden Haghikia   +5 more
doaj   +1 more source

Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 [PDF]

Vojnosanitetski Pregled, 2013
Background/Aim. Tremendous breakthrough in solid organ transplantation was made with the introduction of calcineurin inhibitors (CNI). At the same time, they are potentially nephrotoxic drugs with influence on onset and progression of renal graft ...
Ignjatović Ljiljana, Hrvačević Rajko, Jovanović Dragan, Kovačević Zoran, Vavić Neven, Rabrenović Violeta, Tomić Aleksandar, Aleksić Predrag, Drašković-Pavlović Biljana, Dujić Aleksandar, Karan Željko, Maksić Đoko   +11 more
doaj   +1 more source

HERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician's choice plus trastuzumab in patients with previously treated, anthracycline-naïve, HER2-positive, locally advanced/metastatic breast cancer. [PDF]

, 2016
BackgroundHuman epidermal growth factor receptor 2 (HER2)-positive breast cancer is a particularly aggressive form of the disease, and ultimately progresses in patients with metastases on standard therapies.
Cortes, Javier, Hurvitz, Sara A, Krop, Ian E, Miller, Kathy, Molnar, Istvan, Reynolds, Joseph G, Riahi, Kaveh, Tripathy, Debu, Verma, Sunil, Wickham, Thomas J, Yardley, Denise A   +10 more
core   +2 more sources

Expression of p63 as predictive and prognostic factor in advanced non-small-cell lung cancer [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Serbia belongs to the group of countries with a high lung cancer incidence and mortality rate. p63 gene plays an important role in development of lung cancer and immunohistochemical expression of p63 is considered to be a reliable marker ...
Cvetković Gordana, Plavec Goran, Tatomirović Željka, Jović Milena, Lončarević Olivera, Trifunović Zoran, Vuković Jelena, Stojsavljević Marko, Milić Gordana   +8 more
doaj   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard, B Beutler, B Courtioux, B Namangala, CA Hunter, CA Hunter, CF Calvo, EN Benveniste, F Checchi, F Esamai, G Binz, H Reiber, H Reiber, H Reiber, Hansotto Reiber, HY Hassan, J Kabore, J Rodgers, Jeremy M. Sternberg, JM Sternberg, JM Sternberg, JM Sternberg, Joseph Mathu Ndung'u, KW Moore, L Maclean, L MacLean, L MacLean, L MacLean, LJ Morrison, LM MacLean, Lorna MacLean, M Sjogren, MC Okomo-Assoumou, P Cattand, PD Eckersall, Peter G. E. Kennedy, PG Kennedy, PGE Kennedy, PGE Kennedy, TN Baral, V Jamonneau, V Lejon, V Lejon, V Lejon, W Masocha   +44 more
core   +4 more sources

Histamine index and clinical expression of rheumatoid arthritis activity [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Many arguments prove the pathophysiologic role of histamine in the process of remodeling and joint destruction in rheumatoid arthritis.
Tomić-Lučić Aleksandra P., Pantović Suzana B., Rosić Gvozden L., Obradović Zdravko M., Rosić Mirko A.   +4 more
doaj   +1 more source

Combined population dynamics and entropy modelling supports patient stratification in chronic myeloid leukemia [PDF]

, 2016
Modelling the parameters of multistep carcinogenesis is key for a better understanding of cancer progression, biomarker identification and the design of individualized therapies.
Brehme, Marc, Brümmendorf, Tim H,, Copland, Mhairi, Koschmieder, Steffen, Montazeri, Maryam, Oehler, Vivian G., Radich, Jerald P., Schuppert, Andreas   +7 more
core   +1 more source

Apathy in Alzheimer's disease: Contribution to a clinical view on progression of dementia

Dementia & Neuropsychologia
In addition to cognitive impairment, apathy is increasingly recognized as an important neuropsychiatric syndrome in Alzheimer's disease (AD). Aims: To identify the relationship between dementia severity and apathy levels, and to discuss the association ...
Florindo Stella, Larissa Pires de Andrade, Thays Martins Vital, Flávia Gomes de Melo Coelho, Carla Manuela Crispim Nascimento, Salma Stephany Soleman Hernández   +5 more
doaj   +1 more source

Drosophila as a Model Organism in Host–Pathogen Interaction Studies

Frontiers in Cellular and Infection Microbiology, 2020
Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated.
Salma Younes, Asma Al-Sulaiti, Elham Abdulwahab Ahmed Nasser, Hoda Najjar, Layla Kamareddine   +4 more
doaj   +1 more source