Progression of Coronary Artery Calcium and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis. [PDF]
BackgroundAlthough the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated.
Ambale-Venkatesh, Bharath +9 more
core +2 more sources
Ketogenic diet and fasting diet as Nutritional Approaches in Multiple Sclerosis (NAMS): protocol of a randomized controlled study [PDF]
BACKGROUND: Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system in young adults that may lead to progressive disability.
Bahr, Lina Samira +12 more
core +2 more sources
Evaluating Alzheimer’s disease progression by modeling crosstalk network disruption
Aβ, tau and P-tau have been widely accepted as reliable markers for Alzheimer’s disease (AD). The crosstalk between these markers forms a complex network. AD may induce the integral variation and disruption of the network.
Haochen eLiu +3 more
doaj +1 more source
The potential for dietary factors to prevent or treat osteoarthritis [PDF]
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping +8 more
core +1 more source
Susceptibility to oxidative stress, insulin resistance, and insulin secretory response in the development of diabetes from obesity [PDF]
Background/Aim. Oxidative stress plays a critical role in the pathogenesis of various diseases. Recent reports indicate that obesity may induce systemic oxidative stress.
Kocić Radivoj +3 more
doaj +1 more source
A dynamic network approach for the study of human phenotypes [PDF]
The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases.
A Barrat +35 more
core +5 more sources
Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives
Elisabeth G Celius,1 Heidi Thompson,2 Maija Pontaga,3 Dawn Langdon,4 Alice Laroni,5 Stanca Potra,6 Trishna Bharadia,7 David Yeandle,8 Jane Shanahan,9 Pieter van Galen,10 Nektaria Alexandri,11 Jürg Kesselring12 1Deparment of Neurology, Oslo ...
Celius EG +11 more
doaj
Predictors for Therapy Response to Intrathecal Corticosteroid Therapy in Multiple Sclerosis
Objective: The autoimmune disease Multiple Sclerosis (MS) represents a heterogeneous disease pattern with an individual course that may lead to permanent disability.
Katja Vohl +5 more
doaj +1 more source
Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 [PDF]
Background/Aim. Tremendous breakthrough in solid organ transplantation was made with the introduction of calcineurin inhibitors (CNI). At the same time, they are potentially nephrotoxic drugs with influence on onset and progression of renal graft ...
Ignjatović Ljiljana +11 more
doaj +1 more source
Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]
Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Danhof, M +6 more
core +1 more source

