Results 21 to 30 of about 7,373,821 (305)

Synonymous substitution rates predict HIV disease progression as a result of underlying replication dynamics [PDF]

open access: yes, 2007
Upon HIV transmission, some patients develop AIDS in only a few months, while others remain disease free for 20 or more years. This variation in the rate of disease progression is poorly understood and has been attributed to host genetics, host immune ...
Pybus, OG   +37 more
core   +1 more source

Machine Learning Use for Prognostic Purposes in Multiple Sclerosis

open access: yesLife, 2021
The course of multiple sclerosis begins with a relapsing-remitting phase, which evolves into a secondarily progressive form over an extremely variable period, depending on many factors, each with a subtle influence. To date, no prognostic factors or risk
Ruggiero Seccia   +5 more
doaj   +1 more source

Progression of glomerular diseases [PDF]

open access: yesJournal of Internal Medicine, 1994
Abstract. The nature and slope of progression of glomerular diseases is the subject of considerable discussion. The use of renal biopsies has been accompanied by considerable improvement in the classification of glomerular disease. However, the clinical and histological tools available to assess prognosis in individual patients lack accuracy ...
E P, Peten, L J, Striker
openaire   +2 more sources

Utility of laboratory and immune biomarkers in predicting disease progression and mortality among patients with moderate to severe COVID-19 disease at a Philippine tertiary hospital

open access: yesFrontiers in Immunology, 2023
PurposeThis study was performed to determine the clinical biomarkers and cytokines that may be associated with disease progression and in-hospital mortality in a cohort of hospitalized patients with RT-PCR confirmed moderate to severe COVID-19 infection ...
Felix Eduardo R. Punzalan   +27 more
doaj   +1 more source

Prolonged survival of patients receiving trastuzumab beyond disease progression for HER2 overexpressing metastatic breast cancer (MBC) [PDF]

open access: yes, 2005
Background: The aim of this retrospective analysis was to evaluate the impact of trastuzumab-based regimens on the survival of patients with HER2-overexpressing metastatic breast cancer (MBC).
Heinrich, B.   +5 more
core   +1 more source

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. [PDF]

open access: yes, 2009
Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been
Weber, Bernhard H. F.   +68 more
core   +2 more sources

Landscape analysis for a neonatal disease progression model of bronchopulmonary dysplasia: Leveraging clinical trial experience and real-world data

open access: yesFrontiers in Pharmacology, 2022
The 21st Century Cures Act requires FDA to expand its use of real-world evidence (RWE) to support approval of previously approved drugs for new disease indications and post-marketing study requirements.
Jeffrey S. Barrett   +11 more
doaj   +1 more source

A systematic review of biomarkers for disease progression in Alzheimer's disease [PDF]

open access: yes, 2014
Peer ...
Wright, David E   +44 more
core   +1 more source

Progression of Liver Diseases [PDF]

open access: yesHepatitis Monthly, 2012
Dear Editor, To date, the knowledge on the natural history of HCV infection and the risk factors associated with progression of liver disease in children is limited. Progressive liver disease, including hepatocellular carcinoma, is rare but has been reported [1].
openaire   +2 more sources

A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity.
Trine Holt Edwin   +11 more
doaj   +1 more source

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