Results 31 to 40 of about 3,107,227 (309)

Classification of Pediatric Asthma: From Phenotype Discovery to Clinical Practice

Frontiers in Pediatrics, 2018
Advances in big data analytics have created an opportunity for a step change in unraveling mechanisms underlying the development of complex diseases such as asthma, providing valuable insights that drive better diagnostic decision-making in clinical ...
Ceyda Oksel, Sadia Haider, Sara Fontanella, Clement Frainay, Clement Frainay, Adnan Custovic   +5 more
doaj   +1 more source

Progression of Coronary Artery Calcium and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2017
BackgroundAlthough the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated.
Ambale-Venkatesh, Bharath, Bahrami, Hossein, Bakhshi, Hooman, Bluemke, David A, Budoff, Matthew, Lima, João AC, Ostovaneh, Mohammad R, Wong, Nathan D, Wu, Colin O, Yang, Xiaoying   +9 more
core   +2 more sources

Evaluating Alzheimer’s disease progression by modeling crosstalk network disruption

Frontiers in Neuroscience, 2016
Aβ, tau and P-tau have been widely accepted as reliable markers for Alzheimer’s disease (AD). The crosstalk between these markers forms a complex network. AD may induce the integral variation and disruption of the network.
Haochen eLiu, Chunxiang eWei, Hua eHe, Xiaoquan eLiu   +3 more
doaj   +1 more source

Stage progression and neurological symptoms in Trypanosoma brucei rhodesiense sleeping sickness: role of the CNS inflammatory response [PDF]

, 2012
Background: Human African trypanosomiasis progresses from an early (hemolymphatic) stage, through CNS invasion to the late (meningoencephalitic) stage.
A Hainard, B Beutler, B Courtioux, B Namangala, CA Hunter, CA Hunter, CF Calvo, EN Benveniste, F Checchi, F Esamai, G Binz, H Reiber, H Reiber, H Reiber, Hansotto Reiber, HY Hassan, J Kabore, J Rodgers, Jeremy M. Sternberg, JM Sternberg, JM Sternberg, JM Sternberg, Joseph Mathu Ndung'u, KW Moore, L Maclean, L MacLean, L MacLean, L MacLean, LJ Morrison, LM MacLean, Lorna MacLean, M Sjogren, MC Okomo-Assoumou, P Cattand, PD Eckersall, Peter G. E. Kennedy, PG Kennedy, PGE Kennedy, PGE Kennedy, TN Baral, V Jamonneau, V Lejon, V Lejon, V Lejon, W Masocha   +44 more
core   +4 more sources

Susceptibility to oxidative stress, insulin resistance, and insulin secretory response in the development of diabetes from obesity [PDF]

Vojnosanitetski Pregled, 2007
Background/Aim. Oxidative stress plays a critical role in the pathogenesis of various diseases. Recent reports indicate that obesity may induce systemic oxidative stress.
Kocić Radivoj, Pavlović Dušica, Kocić Gordana, Pešić Milica   +3 more
doaj   +1 more source

MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine. [PDF]

, 2017
The high degree of conservation in microRNA from Caenorhabditiselegans to humans has enabled relatively rapid implementation of findings in model systems to the clinic.
Agarwal, Priyanka, Bhowmick, Neil A, Smith, Bethany   +2 more
core   +1 more source

Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives

Patient Preference and Adherence, 2021
Elisabeth G Celius,1 Heidi Thompson,2 Maija Pontaga,3 Dawn Langdon,4 Alice Laroni,5 Stanca Potra,6 Trishna Bharadia,7 David Yeandle,8 Jane Shanahan,9 Pieter van Galen,10 Nektaria Alexandri,11 Jürg Kesselring12 1Deparment of Neurology, Oslo ...
Celius EG, Thompson H, Pontaga M, Langdon D, Laroni A, Potra S, Bharadia T, Yeandle D, Shanahan J, van Galen P, Alexandri N, Kesselring J   +11 more
doaj  

Predictors for Therapy Response to Intrathecal Corticosteroid Therapy in Multiple Sclerosis

Frontiers in Neurology, 2019
Objective: The autoimmune disease Multiple Sclerosis (MS) represents a heterogeneous disease pattern with an individual course that may lead to permanent disability.
Katja Vohl, Alexander Duscha, Barbara Gisevius, Johannes Kaisler, Ralf Gold, Aiden Haghikia   +5 more
doaj   +1 more source

Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 [PDF]

Vojnosanitetski Pregled, 2013
Background/Aim. Tremendous breakthrough in solid organ transplantation was made with the introduction of calcineurin inhibitors (CNI). At the same time, they are potentially nephrotoxic drugs with influence on onset and progression of renal graft ...
Ignjatović Ljiljana, Hrvačević Rajko, Jovanović Dragan, Kovačević Zoran, Vavić Neven, Rabrenović Violeta, Tomić Aleksandar, Aleksić Predrag, Drašković-Pavlović Biljana, Dujić Aleksandar, Karan Željko, Maksić Đoko   +11 more
doaj   +1 more source

Silent progression in disease activity-free relapsing multiple sclerosis. [PDF]

, 2019
ObjectiveRates of worsening and evolution to secondary progressive multiple sclerosis (MS) may be substantially lower in actively treated patients compared to natural history studies from the pretreatment era.
Baranzini, Sergio E, Barba, Patrick, Bevan, Carolyn, Bischof, Antje, Bove, Riley, Caverzasi, Eduardo, Cree, Bruce AC, Gelfand, Jeffrey M, Gomez, Refujia, Goodin, Douglas S, Graves, Jennifer, Green, Ari J, Gundel, Tristan, Hauser, Stephen L, Henry, Roland G, Hollenbach, Jill A, Kirkish, Gina, Oksenberg, Jorge R, Papinutto, Nico, Ragan, Nicholas R, Romeo, Andrew, Rush, Gillian Q, Sacco, Simone, Santaniello, Adam, Stern, William A, University of California, San Francisco MS-EPIC Team, Wilson, Michael R, Zamvil, Scott S, Zhao, Chao, Zhu, Alyssa H   +29 more
core   +1 more source