FoxO3a and disease progression
World Journal of Biological Chemistry, 2014 The Forkhead box O (FoxO) family has recently been highlighted as an important transcriptional regulator of crucial proteins associated with the many diverse functions of cells. So far, FoxO1, FoxO3a, FoxO4 and FoxO6 proteins have been identified in humans.
Richard Seonghun, Nho, Polla, Hergert
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Susceptibility to oxidative stress, insulin resistance, and insulin secretory response in the development of diabetes from obesity [PDF]
Vojnosanitetski Pregled, 2007 Background/Aim. Oxidative stress plays a critical role in the pathogenesis of various diseases. Recent reports indicate that obesity may induce systemic oxidative stress.
Kocić Radivoj +3 more
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Metabolome in progression to Alzheimer's disease [PDF]
Translational Psychiatry, 2011 Mild cognitive impairment (MCI) is considered as a transition phase between normal aging and Alzheimer's disease (AD). MCI confers an increased risk of developing AD, although the state is heterogeneous with several possible outcomes, including even improvement back to normal cognition.
Hyötyläinen, Tuulia +14 more
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Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives
Patient Preference and Adherence, 2021 Elisabeth G Celius,1 Heidi Thompson,2 Maija Pontaga,3 Dawn Langdon,4 Alice Laroni,5 Stanca Potra,6 Trishna Bharadia,7 David Yeandle,8 Jane Shanahan,9 Pieter van Galen,10 Nektaria Alexandri,11 Jürg Kesselring12 1Deparment of Neurology, Oslo ...
Celius EG +11 more
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Predictors for Therapy Response to Intrathecal Corticosteroid Therapy in Multiple Sclerosis
Frontiers in Neurology, 2019 Objective: The autoimmune disease Multiple Sclerosis (MS) represents a heterogeneous disease pattern with an individual course that may lead to permanent disability.
Katja Vohl +5 more
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Conversion from calcineurin inhibitors to sirolimus of recipients with chronic kidney graft disease grade iii for a period 2003-2011 [PDF]
Vojnosanitetski Pregled, 2013 Background/Aim. Tremendous breakthrough in solid organ transplantation was made with the introduction of calcineurin inhibitors (CNI). At the same time, they are potentially nephrotoxic drugs with influence on onset and progression of renal graft ...
Ignjatović Ljiljana +11 more
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Targeting the Progression of Parkinsons Disease [PDF]
Current Neuropharmacology, 2009 By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion (50-70%) of the cells in the substantia nigra (SN) has already been destroyed. This degeneration progresses until, within a few years, most of the cells have died.
George, JL +6 more
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Expression of p63 as predictive and prognostic factor in advanced non-small-cell lung cancer [PDF]
Vojnosanitetski Pregled, 2018 Background/Aim. Serbia belongs to the group of countries with a high lung cancer incidence and mortality rate. p63 gene plays an important role in development of lung cancer and immunohistochemical expression of p63 is considered to be a reliable marker ...
Cvetković Gordana +8 more
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Cortical hyperexcitability evolves with disease progression in ALS
Annals of Clinical and Translational Neurology, 2020 Cortical hyperexcitability has been established as an early feature of amyotrophic lateral sclerosis (ALS). The evolution of cortical hyperexcitability with ALS progression remains to be fully elucidated.
P. Menon +5 more
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Histamine index and clinical expression of rheumatoid arthritis activity [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. Many arguments prove the pathophysiologic role of histamine in the process of remodeling and joint destruction in rheumatoid arthritis.
Tomić-Lučić Aleksandra P. +4 more
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