Results 61 to 70 of about 13,239,682 (316)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
The Pan African Medical Journal, 2013 INTRODUCTION: Hepatitis B infection impacts negatively on disease progression in HIV infected children thereby increasing morbidity and mortality. In spite of the foregoing, data on Hepatitis B co-infection in children living with HIV in South Eastern ...
Emeka Nwolisa +3 more
doaj +1 more source
Journal of the Formosan Medical Association, 2015 The decoy receptor 3 (DcR3) is a member of the tumor necrosis factor receptor (TNFR) super-family. It counteracts the biological effects of Fas ligands and inhibits apoptosis.
Yu-Ting Lin +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Respiratory ResearchBackground The prognostic value of patterns and quantitative measures of lung fibrosis on high-resolution computed tomography (HRCT) in patients identified as having progressive pulmonary fibrosis (PPF) has not been established.
Aparna C. Swaminathan +8 more
doaj +1 more source
Enhancing glycolysis attenuates Parkinson's disease progression in models and clinical databases.
Journal of Clinical Investigation, 2019 Parkinson's disease (PD) is a common neurodegenerative disease that lacks therapies to prevent progressive neurodegeneration. Impaired energy metabolism and reduced ATP levels are common features of PD.
R. Cai +18 more
semanticscholar +1 more source
Machine learning for comprehensive forecasting of Alzheimer’s Disease progression [PDF]
Scientific Reports, 2018 Most approaches to machine learning from electronic health data can only predict a single endpoint. The ability to simultaneously simulate dozens of patient characteristics is a crucial step towards personalized medicine for Alzheimer’s Disease. Here, we
Charles K. Fisher +24 more
semanticscholar +1 more source
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression [PDF]
Trends in Immunology, 2008 Neurodegenerative diseases are a group of chronic, progressive disorders characterized by the gradual loss of neurons in discrete areas of the central nervous system (CNS). The mechanism(s) underlying their progressive nature remains unknown but a timely and well-controlled inflammatory reaction is essential for the integrity and proper function of the
Hui-Ming, Gao, Jau-Shyong, Hong
openaire +2 more sources
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
JAK/STAT pathway: Extracellular signals, diseases, immunity, and therapeutic regimens
Frontiers in Bioengineering and Biotechnology, 2023 Janus kinase/signal transduction and transcription activation (JAK/STAT) pathways were originally thought to be intracellular signaling pathways that mediate cytokine signals in mammals.
Qian Hu +15 more
doaj +1 more source