Results 71 to 80 of about 7,373,821 (305)

Discovery of a Novel Leaf Rust (Puccinia recondita) Resistance Gene in Rye (Secale cereale L.) Using Association Genomics

Cells, 2021
Leaf rust constitutes one of the most important foliar diseases in rye (Secale cereale L.). To discover new sources of resistance, we phenotyped 180 lines belonging to a less well-characterized Gülzow germplasm at three field trial locations in Denmark ...
Nikolaj Meisner Vendelbo, Khalid Mahmood, Pernille Sarup, Mogens S. Hovmøller, Annemarie Fejer Justesen, Peter Skov Kristensen, Jihad Orabi, Ahmed Jahoor   +7 more
doaj   +1 more source

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Gray matter atrophy rate as a marker of disease progression in AD [PDF]

, 2010
Global gray matter (GM) atrophy rates were quantified from magnetic resonance imaging (MRI) over 6- and 12-month intervals in 37 patients with Alzheimer's disease (AD) and 19 controls using: (1) nonlinear registration and integration of Jacobian values ...
Miller, David H., Nick C. Fox, Kelvin K. Leung, David H. Miller, Anderson, V.M., Anderson, Valerie M, Jonathan W. Bartlett, Leung, Kelvin K, Bartlett, J.W., Bartlett, Jonathan W., Leung, Kelvin K., Fox, Nick C, Schott, Jonathan M, Leung, K.K., Fox, Nick C., Schott, Jonathan M., Valerie M. Anderson, Fox, N.C., Anderson, Valerie M., Schott, J.M., Bartlett, Jonathan W, Jonathan M. Schott, Miller, David H, Miller, D. H., Schott, JM, Fox, NC, Leung, KK, Miller, DH, Anderson, Valerie, Bartlett, JW   +29 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression [PDF]

, 2009
Background: New methods for identifying bladder cancer (BCa) progression are required. Gene expression microarrays can reveal insights into disease biology and identify novel biomarkers.
Wild, P J, Hartmann, A, Wild, PJ, Rehman, I., Stoehr, R, Wild, P.J., Knüchel-Clarke, Ruth, Burger, Maximilian, Rosario, D.J., Hartmann, Arndt, Linkens, D.A., Rehman, I, Abbod, Maysam F., Hamdy, Freddie C., Wild, Peter Johannes, Knuechel, R, Rehman, Ishtiaq, Rosario, Derek J., Knuechel, Ruth, Hartmann, A., Hamdy, F.C., Pilarsky, Christian, Pilarsky, C., Burger, M, Hamdy, FC, Catto, JW, Catto, J W F, Catto, J.W.F., Rosario, DJ, Stöhr, Robert, Wild, Peter J., Linkens, D A, Pilarsky, C, Abbod, M F, Abbod, MF, Hamdy, F C, Burger, M., Rosario, D J, Denzinger, Stefan, Catto, James W.F., Abbod, M.F., Denzinger, S., Hamdy, Freddie, Linkens, Derek A., Stoehr, R., Knuechel, R., Catto, JWF, Catto, James W. F., Denzinger, S, Linkens, DA, Stoehr, Robert   +50 more
core   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

A Nomogram Model of Radiomics and Satellite Sign Number as Imaging Predictor for Intracranial Hematoma Expansion

Frontiers in Neuroscience, 2020
BackgroundWe aimed to construct and validate a nomogram model based on the combination of radiomic features and satellite sign number for predicting intracerebral hematoma expansion.MethodsA total of 129 patients from two institutions were enrolled in ...
Wen Xu, Zhongxiang Ding, Yanna Shan, Wenhui Chen, Zhan Feng, Peipei Pang, Qijun Shen   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Association Between Polygenic Risk Score and the Progression from Mild Cognitive Impairment to Alzheimer's Disease.

, 2021
Mild cognitive impairment (MCI) is a heterogeneous condition and MCI patients are at increased risk of progression to dementia due to Alzheimer's disease (AD). In this study, we aim to evaluate the associations between polygenic risk scores (PRSs) and 1)
Lutz, Michael, Liu, Hongliang, Luo, Sheng, Alzheimer’s Disease Neuroimaging Initiative   +3 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source