Results 191 to 200 of about 1,587,717 (295)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

First High-Density Linkage Map and Quantitative Trait Loci for Disease Resistance in Striped Catfish Pangasianodon hypophthalmus. [PDF]

Int J Mol Sci
Vu NT, Phuc TH, Huong TTM, Nguyen NH.
europepmc   +1 more source

Neuroprotective role of pioglitazone in reversing hippocampal insulin resistance in Amyloid-β fibrils induced animal model of Alzheimer's disease

, 2019
Syed Obaidur Rahman, Suhel Parvez, Bibhu Prasad Panda, Abul Kalam Najmi   +3 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Genome-wide identification and evolutionary analysis of disease resistance genes in Brassica carinata. [PDF]

Plant Genome
Amas JC, Bayer PE, Tan WH, Cantila A, Dolatabadian A, Thomas WJW, Edwards D, Batley J.   +7 more
europepmc   +1 more source

Antibiotic Resistance in Sputum Isolates ofStreptococcus pneumoniaein Chronic Obstructive Pulmonary Disease is Related to Antibiotic Exposure [PDF]

, 2010
Himanshu Desai, Sandra S. Richter, Gary V. Doern, Kris P. Heilmann, Cassie L. Dohrn, Antoinette Johnson, Aimee L. Brauer, Timothy F. Murphy, Sanjay Sethi   +8 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Effects of Methyl Jasmonate on Fruit Quality and Disease Resistance of Mechanically Injured Banana Fruit During Storage. [PDF]

Food Sci Nutr
Huang F, Fan Z, Yi P, Huang M, Gan T, Long Y, Xie L, Li L, Zhang L, Dong H, Wei Q.   +10 more
europepmc   +1 more source

Endophytes Infection Increased the Disease Resistance of Host Achnatherum Sibiricum and Non-Symbiotic Neighbours to Pathogenic Fungi

Xinjian Shi, Jingxin Zhang, Tianzi Qin, Jinming Liu, Yubao Gao, Anzhi Ren   +5 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source