Results 131 to 140 of about 828,302 (264)

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +8 more
wiley   +1 more source

Limited overlap between genetic effects on disease susceptibility and disease survival. [PDF]

open access: yesNat Genet
Yang Z   +26 more
europepmc   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh   +8 more
wiley   +1 more source

New functions of oxylipins released by pyroptotic cells

open access: yesActa Pharmaceutica Sinica B
Hui Xu   +5 more
doaj   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs   +15 more
wiley   +1 more source

Genetic determinants of monocyte splicing are enriched for disease susceptibility loci. [PDF]

open access: yesNat Commun
Nassiri I   +8 more
europepmc   +1 more source

Genetic susceptibility to multifactorial diseases [PDF]

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1997
openaire   +3 more sources

Does COMT Play a Role in Parkinson's Disease Susceptibility across Diverse Ancestral Populations? [PDF]

open access: yesMov Disord
Martín-Bórnez M   +16 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy