Results 11 to 20 of about 296,939 (346)
From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis
Blood comprises a wide array of specialized cells, all of which share the same genetic information and ultimately derive from the same precursor, the hematopoietic stem cell (HSC).
Roger Mulet-Lazaro, Ruud Delwel
doaj +1 more source
A Question of Frame: The Role of the Bone Marrow Stromal Niche in Myeloid Malignancies
Until a few years ago, the onset of acute myeloid leukemia (AML) was entirely ascribed to genetic lesions in hematopoietic stem cells. These mutations generate leukemic stem cells, which are known to be the main ones responsible for chemoresistance and ...
Chiara Tomasoni +4 more
doaj +1 more source
Few epidemiologic studies have examined the role of maternal iron status in allergic diseases in offspring and findings have been inconsistent. We used a large birth cohort in Japan to explore the association of the markers for maternal iron status ...
Limin Yang +12 more
semanticscholar +1 more source
Central nervous system cholesterol metabolism in health and disease
Cholesterol is a ubiquitous and essential component of cellular membranes, as it regulates membrane structure and fluidity. Furthermore, cholesterol serves as a precursor for steroid hormones, oxysterol, and bile acids, that are essential for maintaining
W. Y. Ho, H. Hartmann, Shuo-Chien Ling
semanticscholar +1 more source
Impact of SARS-CoV-2 infection on patients with hematological malignancies: a retrospective study
Objectives This study aimed to evaluate the characteristics of patients with hematological malignancies (HM) and SARS-CoV-2 infection and analyze the risk factors of their severity and mortality.Methods A retrospective study including inpatients ...
Huihan Zhao +5 more
doaj +1 more source
Adult Incidence in the Russian European Arctic with Developed Mining and Metallurgical Industry (en)
The purpose of the research. The research aims to assess the adult incidence within the mining complex in the Murmansk Region (the Russian Arctic). Materials and methods.
A. N. Nikanov +4 more
doaj +1 more source
Diseases of the poultry reproductive organs (Case study: Altai Region, Russia) [PDF]
We carried out a complex research on the determination of pathogenesis and etiology of diseases of egg-forming organs in laying hens in conditions of industrial breeding.
Sergey V. Fedotov +2 more
doaj +1 more source
Natural water supply of the Republic of Kalmykia does not meet the needs of industrial, agricultural and social needs. Kalmykia, due to its geographical position, is turned into the utilizer of chemically polluted waters and industrial effluents ...
Nastinova Galina Erdneevna +1 more
doaj +1 more source
Homeostasis as the Mechanism of Evolution. [PDF]
Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
core +2 more sources
Systemic sclerosis (SSc) is a systemic disease characterized by autoimmune responses, vasculopathy and tissue fibrosis. The pathogenic mechanisms involve a wide range of cells and soluble factors.
E. Xue +5 more
semanticscholar +1 more source

