Results 41 to 50 of about 161,125 (296)

ЗАГАЛЬНА ХАРАКТЕРИСТИКА ЗАХВОРЮВАЛЬНОСТІ ДИТЯЧОГО НАСЕЛЕННЯ УКРАЇНИ ТА ПОШИРЕНОСТІ СЕРЕД ДІТЕЙ ХВОРОБ [PDF]

, 2023
The dynamics of changes in indices of children morbidity in Ukraine and the prevalence of diseases among them for 2010-2014 is presented. Decrease of indices of morbidity among children and prevalence of diseases among them is determined in all main ...
Слабкий, Г.О., Знаменська, М.А.   +1 more
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Costs of hospital admission on primary immunodeficiency diseases [PDF]

, 2017
Background: Primary immunodeficiency diseases (PID) are heterogeneous group of inherited disorders mainly characterized by recurrent infections leading to several times hospital admissions.
Javadi, Mohammad Reza, Rezaei, Nima, Abolhassani, Hassan, Aghamohammadi, Asghar, Ahmadvand, Alireza, Gholami, Kheirollah, Laali, Elaheh, Mohebbi, Niayesh   +7 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Risk factors for ADRs in the two study cohorts (results of the multivariable regression analysis).^†*

, 2013
*full models were adjusted by possible confounding factors (age, gender, number of diagnosis, length of stay, number of drugs prescribed, and diseases.**D = Diseases of the blood, the blood-forming organs and certain immune deficiencies;***Q = Congenital
Asia N. Rashed (306888), Ian C. K. Wong (306894), Antje Neubert (306897), Barbara Hefele (306891), Ann-Kathrin Oehme (306885), Wolfgang Rascher (299647)   +5 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The human health risk assessment from contaminated air in the oil-producing areas (on the example of Novoshehminsky Region of the Republic of Tatarstan)

, 2020
© 2014 AENSI Publisher All rights reserved. Based on the analysis of the monitoring results the air quality evaluation is provided and the incidence level of oil-producing Novosheshminsky region of the Republic of Tatarstan during the period of 2005-2009.
Novikova L., Stepanova N., Latypova V.
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