Results 81 to 90 of about 3,014,077 (337)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

The Cost of Care: New Insights into Healthcare Spending Growth [PDF]

open access: yes, 2017
[Excerpt] The Bureau of Labor Statistics (BLS) is celebrating the first anniversary of experimental disease-based price indexes, which adjust expenditures on disease for inflation.
Bradley, Ralph
core   +1 more source

Development of Bone Targeting Drugs. [PDF]

open access: yes, 2017
The skeletal system, comprising bones, ligaments, cartilage and their connective tissues, is critical for the structure and support of the body. Diseases that affect the skeletal system can be difficult to treat, mainly because of the avascular cartilage
Alméciga-Díaz, Carlos J.   +6 more
core   +2 more sources

Bilineal acute leukemia: a rare expression of common ALL markers and pre-T markers Leucemia aguda bilineal: marcadores e pre T marcadores, uma rara expressão na leucemia aguda linfoblástica comum

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2005
In this case report the case of bilineal acute leukemia with a rare expression of common ALL and pre-T markers is presented. The cytogenetic and immunophenotypic clinical aspects of a 38-year-old male patient are described.Neste relato é apresentado um ...
Fernando Callera
doaj   +1 more source

Oscillations in a maturation model of blood cell production [PDF]

open access: yesarXiv, 2004
In this paper we use a continuous model to describe the development of a single cell lineage following the committal of stem cells. Three separate controls are implemented in the model, namely the proliferative control of stem cells, the proliferative control of developing blast cells, and the peripheral control of stem cell committal by circulating ...
arxiv  

Venous compression causes chronic cerebral ischaemia in normal pressure hydrocephalus patients

open access: yesFluids and Barriers of the CNS
Background Cerebral autoregulation is a robust regulatory mechanism that stabilizes cerebral blood flow in response to reduced blood pressure, thereby preventing cerebral ischaemia.
Tomohisa Ohmura   +13 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Factors influencing transfusion requirement in patients undergoing first-time, elective coronary artery bypass graft surgery

open access: yesAsian Journal of Transfusion Science, 2017
Context: Coronary artery bypass graft (CABG) operation is associated with high frequency of allogeneic blood transfusion due to the acquired hemostatic challenges in patients undergoing CABG.
Ailin Mazuita Mazlan   +4 more
doaj   +1 more source

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease. [PDF]

open access: yes, 2018
Sexual transmission of Ebola virus (EBOV) has been demonstrated more than a year after recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying EBOV persistence and sexual transmission are not currently understood.
Bernbaum, John G.   +7 more
core   +1 more source

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