Results 91 to 100 of about 135,123 (304)

The Effect of Drug Vintage on Survival: Micro Evidence from Puerto Rico's Medicaid Program [PDF]

Using micro data on virtually all of the drugs and diseases of over 500,000 people enrolled in Puerto Rico's Medicaid program, we examine the impact of the vintage (original FDA approval year) of drugs used to treat a patient on the patient's 3-year ...
Frank R. Lichtenberg
core  

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Impaired fertility and reproductive function in patients with complicated forms of inflammatory diseases of the genitourinary system [PDF]

, 2015
Marat Askhakov, Vyacheslav Chebotarev, Natalya Chebotareva, Islam Lajpanov   +3 more
openalex   +3 more sources

Exploring the potential mechanisms of impairment on genitourinary system associated with coronavirus disease 2019 infection: Bioinformatics and molecular simulation analyses

, 2023
Kai Zhao, Dong Zhang, Xinchi Xu, Shangqian Wang, Zhanpeng Liu, Xiaohan Ren, Xu Zhang, Zhongwen Lù, Shancheng Ren, Chao Qin   +9 more
openalex   +1 more source

MARCO+ Tumor‐Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma

Advanced Science, EarlyView.
MARCO+ TAMs dominate restrained cytotoxicity of CD8+ CTLs and ICB resistance in RCC. Mechanically, MARCO impairs MHC‐I‐mediated neoantigen cross‐presentation via the SOCS1‐JAK1‐STAT1‐NLRC5 signaling cascade in TAMs. Targeted MARCO treatment boosts macrophage antigen cross‐presentation and empowers CD8+ T cells, thereby potentiating ICB efficacy ...
Jiayuan Chen, Jiazhi Mo, Jinchang Wei, Mengnan Qu, Jie Dai, Yan Kong, Huayan Xu, Juan Li, Xieqiao Yan, Chuanliang Cui, Lu Si, Zhihong Chi, Jun Guo, Xiaowen Wu, Xinan Sheng   +14 more
wiley   +1 more source

Renal manifestations of brucellosis: a case report

Journal of Medical Case Reports
Background Brucellosis is one of the most prevalent zoonotic diseases worldwide, posing a significant public health concern across both developed and developing nations.
Zahra Ghavami, Bezat Amiri, Mahboubeh Haddad, Farzaneh Khoroushi, Farshad Abedi, Sepideh Elyasi, Fereshte Sheybani   +6 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1970
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1060/thumbnail ...

core   +1 more source

Aptamer‐Engineered Ellipsometry for Clinical Detection of BALF‐Derived Exosomes: Multi‐Level Engineering for Prognostic Evaluation of Immunotherapy Responses

Advanced Science, EarlyView.
A novel ellipsometry platform functionalized with truncated PD‐L1 aptamers are developed to enable ultrasensitive detection of BALF‐derived exosomes. Through chemical ligand tailoring, mechanical sensing optimization, and tumor‐proximal fluid sampling, the system precisely stratifies ICI responders and non‐responders, offering superior sensitivity and ...
Euna Jeong, Jung Hyun Choi, Minyoung Lee, Jun Hyeok Lim, Seokho Jung, Yeeun Woo, Joo‐young Kim, Jaehyeon Ok, Lucia Kim, Woo‐jin Jeong, Won Chegal, Hyun Mo Cho, Chulhwan Park, Jiyoon Bu, Dong Hyung Kim, Taek Lee   +15 more
wiley   +1 more source

FACTORS THAT DETERMINE THE OUTCOME OF PREGNANCY AND HEALTH OF CHILDREN BORN TO WOMEN WITH GENITOURINARY SYSTEM DISEASES USING ASSISTED REPRODUCTIVE TECHNOLOGIES

, 2021
Anna N. Plaksina, O. P. Kovtun, Svetlana L. Sinotova, O. V. Limanovskaya, Valeriya A. Makutina   +4 more
openalex   +1 more source

Solar‐Powered Electrokinetic Filtration using Hierarchical Porous Membranes for the Off‐Grid Removal of Ultrafine Contaminants

Advanced Science, EarlyView.
A solar‐powered nanoelectrokinetic filtration system enables high‐flux removal of ultrafine contaminants without relying on nanoscale pores or pressure‐driven membranes, offering a sustainable solution for the off‐grid water purification. Abstract The removal of ultrafine suspended solids from water remains a critical challenge due to the tradeoffs ...
Woonjae Choi, Minsoo Lee, Young June Park, Seungbin Yoon, Geunbae Lim   +4 more
wiley   +1 more source