Results 51 to 60 of about 135,123 (304)

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Risk of cerebral palsy and childhood epilepsy related to infections before or during pregnancy.

PLoS ONE, 2013
Background and aimMaternal infections during pregnancy have been associated with several neurological disorders in the offspring. However, given the lack of specificity for both the exposures and the outcomes, other factors related to infection such as ...
Chun S Wu, Lars H Pedersen, Jessica E Miller, Yuelian Sun, Elani Streja, Peter Uldall, Jørn Olsen   +6 more
doaj   +1 more source

A Self‐Curling Si3N4‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

Advanced Functional Materials, EarlyView.
Si3N4‐enhanced bioactive nanostructured adhesive wrap enables rapid conduit formation in wet environments, simplifying surgical procedures. Incorporated Si3N4 undergoes controlled hydrolysis within nanofibers, multi‐directionally modulating the peripheral nerve repair microenvironment for effective suture‐free repair.
Pengchao Ma, Yihao Liu, Bowen Ren, Chun‐Yi Yang, Xiaobin Luo, Peilun Hu, Jia Yang, Zheng Cao, Keya Mao, Jianheng Liu, Xiumei Wang   +10 more
wiley   +1 more source

Collagen-based materials in male genitourinary diseases and tissue regeneration

Collagen and Leather
Male genitourinary dysfunction causes serious physical or mental distress, such as infertility and psychological harm, which leads to impaired quality of life.
Fangyuan Li, XinHuang, Ruiying Wang, Yujing Li, Lukanxuan Wu, Xinyu Qiao, Yuchan Zhong, Guidong Gong, Wei Huang   +8 more
doaj   +1 more source

Spreading of diseases through comorbidity networks across life and gender [PDF]

, 2014
The state of health of patients is typically not characterized by a single disease alone but by multiple (comorbid) medical conditions. These comorbidities may depend strongly on age and gender.
Chmiel, Anna, Klimek, Peter, Thurner, Stefan   +2 more
core   +2 more sources

Crack‐Growing Interlayer Design for Deep Crack Propagation and Ultrahigh Sensitivity Strain Sensing

Advanced Functional Materials, EarlyView.
A crack‐growing semi‐cured polyimide interlayer enabling deep cracks for ultrahigh sensitivity in low‐strain regimes is presented. The sensor achieves a gauge factor of 100 000 at 2% strain and detects subtle deformations such as nasal breathing, highlighting potential for minimally obstructive biomedical and micromechanical sensing applications ...
Minho Kim, Taewi Kim, Jieun Park, Insic Hong, Myungrae Hong, Seonggyeong Park, Beomjin Kim, Sehyuk Ahn, Siwoo Jang, Seungyong Han, Je‐Sung Koh, Daeshik Kang   +11 more
wiley   +1 more source

Ambient air pollution and cause-specific risk of hospital admission in China: A nationwide time-series study.

PLoS Medicine, 2020
BackgroundThe impacts of air pollution on circulatory and respiratory systems have been extensively studied. However, the associations between air pollution exposure and the risk of noncommunicable diseases of other organ systems, including diseases of ...
Jiangshao Gu, Ying Shi, Yifang Zhu, Ning Chen, Haibo Wang, Zongjiu Zhang, Ting Chen   +6 more
doaj   +1 more source

Testing for sexually transmitted infections among students: a discrete choice experiment of service preferences [PDF]

, 2013
Objectives To assess preferences among students for sexually transmitted infection (STI) testing services, with a view to establishing strength of preference for different service attributes.
Lagarde, Mylene, Llewellyn, Carrie D, Miners, Alec H, Pollard, Alex, Sakal, Chloe   +4 more
core   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Induction of Nephron–Ductal Dual Lineages via Early Retinoic Acid Signaling Establishes a Platform for Fully Patterned Kidney Organoids

Advanced Healthcare Materials, EarlyView.
A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim, Seeun Kim, Dong Hyun Lee, Dae Hun Kim, Hye Bin Lee, Ye Seul Son, Mi‐Young Son, Soo Jin Oh, Ji‐Yoon Lee, Mi‐Ok Lee, Hyun Soo Cho, Dae‐Soo Kim, Cho‐Rok Jung, Hyun Mi Kang   +13 more
wiley   +1 more source