Results 81 to 90 of about 135,123 (304)

Assessing somatization in urologic chronic pelvic pain syndrome [PDF]

open access: yes, 2019
BACKGROUND: This study examined the prevalence of somatization disorder in Urological Chronic Pelvic Pain Syndrome (UCPPS) and the utility of two self-report symptom screening tools for assessment of somatization in patients with UCPPS.
Alpers, D H   +3 more
core   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

open access: yesAdvanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu   +16 more
wiley   +1 more source

Dynamics and tendency of sick rate in children of urban areas with different quality of the atmospheric air

open access: yesRUDN Journal of Medicine, 2016
In the article there are results of the comparative analysis of dynamics and tendencies of main diseases incidence in children constantly living in the city districts characterizing by different quality of the atmospheric air.
A A Dementyev   +3 more
doaj  

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

open access: yesAdvanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan   +10 more
wiley   +1 more source

Robust Physics‐Informed Neural Network Approach for Estimating Heterogeneous Elastic Properties from Noisy Displacement Data

open access: yesAdvanced Science, EarlyView.
Heterogeneous distributions of elasticity parameters are learned from noisy displacement data using the Inverse Elasticity Physics‐Informed Neural Network (IE‐PINN). This approach integrates both data‐driven and physics‐driven methods to address the significant limitations faced by existing techniques.
Tatthapong Srikitrungruang   +4 more
wiley   +1 more source

ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
In clear cell renal cell carcinoma, estrogen receptor β (ERβ) upregulates circAHNAK, which competitively binds USP10 to prevent FMR1 deubiquitination, leading to FMR1 degradation. Loss of FMR1 hinders m⁶A‐dependent decay of ADAM17 mRNA, resulting in ADAM17 accumulation in tumor exosomes and enhanced angiogenesis.
Chao Xu   +14 more
wiley   +1 more source

Report of one case with de novo mutation in TLK2 and literature review

open access: yesBMC Pediatrics
TLK2 variants were identified as the cause for several neurodevelopmental disorders by impacting brain development. The incidence of mutation in TLK2 is low, which has common clinical features with other rare diseases.
Han-Yue Li   +3 more
doaj   +1 more source

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

open access: yesAdvanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu   +23 more
wiley   +1 more source

Adult Incidence in the Russian European Arctic with Developed Mining and Metallurgical Industry (en)

open access: yesРоссийская Арктика, 2019
The purpose of the research. The research aims to assess the adult incidence within the mining complex in the Murmansk Region (the Russian Arctic). Materials and methods.
A. N. Nikanov   +4 more
doaj   +1 more source

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