Brain-invading monocytes promote seizure-associated cognitive deficits and neurodegeneration. [PDF]
Pourkhodadad S +3 more
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Three-dimensional characteristics of the alveolar capillary network in infant and adult human lungs. [PDF]
Rößler G +4 more
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Sry-modified laboratory rat lines to study sex-chromosome effects underlying sex differences in physiology and disease: Four Core Genotypes and more. [PDF]
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Exploring alveolar recruitability using positive end-expiratory pressure in mice overexpressing TGF-β1: a structure-function analysis. [PDF]
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Blood flow patterns in mice are regulated by interpericyte tunneling nanotubes connecting functionally-opposite neuronal areas. [PDF]
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Estimating the number of granule cells in the dentate gyrus with the disector
Brain Research, 1988A practical example is given of how a newly developed stereological estimator of particle number, the disector, can be used to make estimates of neuron number in the dentate gyrus of rats. The estimates are free of biases related to lost caps, overprojection and assumptions about size, shape and orientation of the objects that are counted. The disector
Mark J West +2 more
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Practical considerations for the use of the optical disector in estimating neuronal number
Journal of Neuroscience Methods, 1994The aim of this study was to establish methodological variability in the estimation of the total number of neurones using the optical disector. Variations in the 3 dimensions of the disector probe were analysed under uniform sampling conditions in 50-microns-thick frozen sections of the human mediodorsal thalamic nucleus.
A J Harding, Glenda M Halliday
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The revolution of counting “tops”: Two decades of the disector principle in morphological research
Microscopy Research and Technique, 2005AbstractTwenty years have passed since the publication of the seminal paper enunciating the disector principle by an author using the pseudonym D.C. Sterio. During this time, methods based on the revolutionary principle of counting “tops” have become progressively better known and have been included in several commercially available systems for ...
Stefano Geuna
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Reliability and validity of the physical disector method for estimating neuron number
Journal of Neurobiology, 1996The physical disector was proposed as an unbiased and efficient means to estimate neuron number; however, the validity and reliability of this method have been examined only infrequently. Estimates of neuron number in the dorsal root ganglia (DRG) of bullfrogs (Rana catesbeiana) were compared to nucleolar counts based on 3-dimensional reconstructions ...
Paul B Farel
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