Absolute Number of Thalamic Parafascicular and Striatal Cholinergic Neurons, and the Three-Dimensional Spatial Array of Striatal Cholinergic Neurons, in the Sprague-Dawley Rat. [PDF]
J Comp NeurolThe absolute numbers of thalamic parafascicular (PFN) neurons and striatal cholinergic interneurons (CIN) were estimated in rats using unbiased stereological methods. Spatial statistical analysis of the three‐dimensional distribution revealed that the large, mostly CIN were randomly positioned with no evidence of clustering.
Zhang R +3 more
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High vulnerability of medial prefrontal pyramidal neurons in post-stroke, vascular, Alzheimer's disease, and aging-related dementias. [PDF]
Alzheimers DementAbstract INTRODUCTION The medial prefrontal cortex (mPFC) is critical for executive function, behavioral inhibition, and memory. Its high vulnerability to dementia, compared to other prefrontal regions, remains unclear. METHODS We analyzed post mortem brain tissue from 118 older subjects, including post‐stroke survivors, Alzheimer's disease; vascular ...
Jobson DD +6 more
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A Regional Ultrastructural Analysis of the Cellular and Synaptic Architecture of the Mouse Vestibular Periphery, With Reference to the Chinchilla. [PDF]
J Comp NeurolSynaptic innervation in mouse inner ear vestibular hair cells has been a topic of interest lately, with the revelation of the importance of non‐quantal transmission in Type I hair cells. Transmission electron microscopy and the dissector sampling method were used to assess synaptic ribbon counts per hair cell.
Ahmad M +7 more
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Automated Euler number of the alveolar capillary network based on deep learning segmentation with verification by stereological methods. [PDF]
J MicroscAbstract Diseases like bronchopulmonary dysplasia (BPD) affect the development of the pulmonary vasculature, including the alveolar capillary network (ACN). Since pulmonary development is highly dependent on angiogenesis and microvascular maturation, ACN investigations are essential.
Schmidt J +5 more
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Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents. [PDF]
Magn Reson MedAbstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Kurniawan ND +11 more
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Image Analysis and Stereology, 2011 The conventional serial sectioning analysis and a set of modern stereological methods, including disector, selector, point-sampled intercepts, point-sampled area, and their combinations, have been used in this paper to measure the grain size, grain size ...
Guoquan Liu, Haibo Yu
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A short primer on lung stereology
Respiratory Research, 2021 The intention of this short primer is to raise your appetite for proper quantitative assessment of lung micro-structure. The method of choice for obtaining such data is stereology.
Matthias Ochs, Julia Schipke
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DISECTOR PROGRAM FOR UNBIASED ESTIMATION OF PARTICLE NUMBER, NUMERICAL DENSITY AND MEAN VOLUME
Image Analysis and Stereology, 2011 A DISECTOR program is presented, offering the possibility to count particles by the disector or unbiased sampling brick principles as well as to apply the point-counting method needed for estimation of the particle volume density or mean particle volume.
Zoltán Tomori +2 more
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Total neuron counts in vulnerable and resilient entorhinal subregions [PDF]
Alzheimers DementAbstract Background Neuron loss exceeds tau tangle formation (Gomez‐Isla et al. 1997) and p‐tau vulnerability differs by layer and subfield in entorhinal cortex (Llamas‐Rodriguez et al., 2022). Some subfields succumb to tau early and other subfields later in Alzheimer’s disease.
Rosenblum E, Augustinack J.
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Image Analysis and Stereology, 2011 Atherosclerosis is a chronic metabolic and inflammatory disease of vascular arteries. Insome cases, it comes the accumulation of the inflammatory cells and extracellular matrix in vessel intima, which lead to the narrowing of the vessel lumen. The aim of
Petr Nachtigal +5 more
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