Results 21 to 30 of about 1,604 (164)

Stereological tools in biomedical research

open access: yesAnais da Academia Brasileira de Ciências, 2003
Stereological studies are more and more frequent in literature, particularly in the development/evolution, pathology, and neurosciences areas. The stereology challenge is to understand the structural inner threedimensional arrangement based on the ...
Carlos A. Mandarim-de-Lacerda
doaj   +1 more source

STEREOLOGICAL ESTIMATION OF ITO CELLS FROM RAT LIVER USING THE OPTICAL FRACTIONATOR - A PRELIMINARY REPORT

open access: yesImage Analysis and Stereology, 2011
In the last two decades, much light has been shed on hepatic fibrosis, and the activation / proliferation of Ito cells (IC) emerged to play a central role.
Ricardo Marcos   +2 more
doaj   +1 more source

Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease

open access: yesFrontiers in Neuroanatomy, 2017
Stereological analysis is the optimal tool for quantitative assessment of brain morphological and cellular changes induced by neurotoxic lesions or treatment interventions.
Katrine Fabricius   +3 more
doaj   +1 more source

METRIC CHARACTERISTICS OF VARIOUS METHODS FOR NUMERICAL DENSITY ESTIMATION IN TRANSMISSION LIGHT MICROSCOPY – A COMPUTER SIMULATION

open access: yesImage Analysis and Stereology, 2011
In the introduction the evolution of methods for numerical density estimation of particles is presented shortly. Three pairs of methods have been analysed and compared: (1) classical methods for particles counting in thin and thick sections, (2) original
Miroslav Kališnik   +3 more
doaj   +1 more source

Quantitative Caveats of Standard Immunohistochemical Procedures: Implications for Optical Disector–based Designs [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 2009
Immunohistochemistry is a ubiquitous technique in histology. Often, the goal of such studies is the quantification of some parameter associated with a particular antigen. When used correctly, the optical disector offers a statistically relevant approach to achieve this goal without bias from cell size, shape, or orientation.
Neal R, Melvin, Robert J, Sutherland
openaire   +2 more sources

Un nuevo dispositivo disector que separa y limpia las estructuras anatómicas durante la cirugía laparoscópica

open access: yesCirugía y Cirujanos
Objetivo: Describir un nuevo dispositivo disector en laparoscopia, con una mejor definición de las estructuras anatómicas para obtener una mejor disección,separación y limpieza de las estructuras.
Luis Padilla   +10 more
doaj   +1 more source

Stereological evaluation of the neuroprotective effects of curcumin on the spinal cord in a streptozotocin-induced diabetic rat model

open access: yesFrontiers in Neuroanatomy
IntroductionThis study examined how curcumin influences spinal cord morphological parameters in rats with STZ-induced diabetes using unbiased stereological methods.MethodsFifty-six female Wistar albino rats were randomly divided into seven experimental ...
Burcu Delibaş   +7 more
doaj   +1 more source

GLOMERULAR NUMBER AND CAPILLARY DIMENSIONS IN THE NORMAL LAMB KIDNEY

open access: yesImage Analysis and Stereology, 2011
Reduced nephron endowment, either inherited or acquired, has been linked to adult renal pathology as well as hypertension. The sheep provides an excellent model for studying nephrogenesis and renal development because, as in humans, nephrogenesis is ...
Julian Brown   +5 more
doaj   +1 more source

Use of the optical disector in canine mammary simple and complex carcinomas

open access: yesAPMIS, 2017
Grading of canine mammary carcinomas (CMC) is associated to subjective assessments made by the pathologists. Due to its unbiased nature, stereology can be used to objectively quantify morphological parameters associated with grading and malignancy. However, the use of stereology in CMC has not been fully disclosed.
Santos, M   +6 more
openaire   +3 more sources

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

open access: yesInternational Journal of Eating Disorders, Volume 59, Issue 5, Page 869-884, May 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang   +9 more
wiley   +1 more source

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