Results 41 to 50 of about 209,845 (305)
A Cross-Sectional Survey on Burnout Prevalence and Profile in the Sicilian Population of Ambulance Driver-Rescuers [PDF]
, 2020 Introduction: Burnout is present at a high rate in emergency medicine. The ambulance driver-rescuers, who furnish first aid to the victims, are the non-medical part of the Italian 118-service staff.
Chifari, Angelo +8 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Conceptualising Gifted Student (Dis) Engagement through the Lens of Learner (Re) Engagement
Education Sciences, 2020 It is well-recognised that disengagement is a growing problem in schools across the globe. Furthermore, statistics show that nearly 60% of all gifted students are not actualising their potential, exposing the loss of potential for both the individual and
Michelle Ronksley-Pavia +1 more
doaj +1 more source
Working-class males and engagement with high school education [PDF]
, 2015 This study explores working-class males' engagement with high school education as statistically this group are underachieving and the chosen city in the North-West of England has been highlighted as an area of particular concern.
Wilson, Matthew
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
European Journal of Turkish Studies, 2014 The uprisings that erupted unexpectedly in the Middle East between 2010 and 2011 propelled this region’s youth to the forefront of the political and media scene.
Jordi Tejel Gorgas
doaj +1 more source
Political Disengagement Among Youth: A Comparison Between 2011 and 2020
Frontiers in Psychology, 2022 This study answers one general question using a country case: what shapes the young generations’ political disengagement in Singapore? Taking the generational differences and institutional influence perspectives, this study highlights the time dimension ...
Weiyu Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Process and Affordances of Platform-Specific Social Media Disconnection
Studies of Transition States and Societies, 2018 This article examines millennials’ experience of platform-specific disconnection, focusing on the ambiguous intersection of engagement and disengagement with social media.
Ramona-Riin Dremljuga
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source