Results 51 to 60 of about 106,495 (292)

Requirements for Diagnosis of Malaria at Different Levels of the Laboratory Network in Africa. [PDF]

, 2009
The rapid increase of resistance to cheap, reliable antimalarials, the increasing cost of effective drugs, and the low specificity of clinical diagnosis has increased the need for more reliable diagnostic methods for malaria.
Barnish, Earl G. Long, Hopkins, Rafael, Redd, World Health Organization   +5 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Biosafety and Biohazards: Understanding Biosafety Levels and Meeting Safety Requirements of a Biobank. [PDF]

, 2019
When it comes to biobanking and working with different types of laboratory specimens, it is important to understand potential biohazards to ensure safety of the operator and laboratory personnel.
Gosa, Laura, Nathanson, David A, Ta, Lisa   +2 more
core   +2 more sources

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Efficacy of chemical disinfectants for the containment of the salamander chytrid fungus Batrachochytrium salamandrivorans [PDF]

, 2017
The recently emerged chytrid fungus Batrachochytrium salamandrivorans (Bsal) causes European salamander declines. Proper hygiene protocols including disinfection procedures are crucial to prevent disease transmission.
Coen, Yanaïka, Martel, An, Pasmans, Frank, Van Rooij, Pascale   +3 more
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Qualitative and quantitative evaluation of bacterial contamination of toothbrushes kept in different sanitary settings: A comparative study

Journal of Indian Association of Public Health Dentistry, 2021
Background: Oral health is an integral part of general health and toothbrushes are the most commonly used oral hygiene aid. Unfortunately, proper care of toothbrush is often neglected and is kept in bathrooms which are a good place to harbor millions of ...
Meenakshi Thakur, Sudhir Mittal, Amit Kumar Sharma, Devender Kumar Sharma, Kamal K Gupta, Vasundhara Pathania   +5 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

The antibacterial performance of a residual disinfectant against Staphylococcus aureus on environmental surfaces

Frontiers in Microbiology
Environmental surfaces play a key role in transmitting pathogens that can survive on surfaces for long durations. The interest in long-lasting or residual disinfectants are, therefore, growing as it might protect surfaces for longer than traditional ...
Soraya Omardien, Sarvesh Pingulkar, Mariska Thayagan, Laura Buniotto, Mateus de Oliveira Negreiros   +4 more
doaj   +1 more source

A Systematic Review of the Evidence for the Sustainability of Household Water Treatment Interventions [PDF]

, 2011
This systematic review assesses the quantity and quality of evidence for the sustainability of household water treatment (HWT) since the World Health Organization (WHO) recently endorsed HWT based on growing evidence of HWT's ability to improve microbial
Karen Levy, William E. Oswald
core