Results 161 to 170 of about 778,589 (272)

Obesity-induced NLRP3 inflammasome activation in nucleus pulposus cells accelerates intervertebral disk degeneration. [PDF]

J Orthop Surg Res
Gao S, Su NN, Zhao Q, Wang FF, Wang SC, Guo W.   +5 more
europepmc   +1 more source

A High‐Efficiency Yet Sustainable Fresh‐Keeping Strategy Inspired by Calyx of Physalis peruviana

Exploration, EarlyView.
This study presents a sprayable, calyx‐inspired food wrap engineered for safety and sustainability using handheld electrospraying. The wrap forms a health‐critical protective barrier with high antiviral and antibacterial efficacy, excellent breathability, and long‐term fresh‐keeping performance.
Yue Zhao, Chengbang Lu, Xiaopeng Bai, Shangyi Wu, Zeyu Wang, Yuqin Hu, Binxin Liang, Danlei Sun, Yunxiang Zhang, Yingning He, Yi Yang, Shengwen Duan, Taolin Sun, Xinjie Wang, Weijie Lan, Hong Zhang, Yang Luo, Xiangyu Liang   +17 more
wiley   +1 more source

Investigating the epigenetic landscape of symptomatic disk degeneration: a case study. [PDF]

Pain Rep
Yeater TD, Kawarai Y, Lee S, Belani KG, Beebe DS, Sheyn D, Pinto MR, Stone LS.   +7 more
europepmc   +1 more source

Effects of Competition Level on the Prevalence and Incidence of Lumbar Disk Degeneration in Japanese Collegiate Gymnasts. [PDF]

Orthop J Sports Med, 2022
Koyama K, Nakazato K, Kubo Y, Gushiken K, Hatakeda Y, Seo K, Nakase T, Hiranuma K.   +7 more
europepmc   +1 more source

Sel1l preserves condylar cartilage matrix homeostasis by regulating PERK signaling

Interdisciplinary Medicine, EarlyView.
Our study revealed that the expression of Sel1l was downregulated in OA cartilage and that Sel1l deficiency induced cartilage catabolism. Mechanistically, Sel1l depletion aberrantly activated PERK signaling and resulted in ER stress. PERK inhibition rescued the phenotype of Sel1l‐deficient chondrocytes and alleviated TMJOA pathogenesis.
Xinqi Huang, Zinan Cen, Zhihe Zhao, Xiao Cen   +3 more
wiley   +1 more source

Druggable Genome-Wide Mendelian Randomization Identifies Distinct Therapeutic Targets for Low Back Pain, Intervertebral Disk Degeneration, and Sciatica. [PDF]

J Pain Res
Sun A, Li Z, Du Y, Liu H, Zhan Q, Liu Z.
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

A new target for treating intervertebral disk degeneration: gut microbes. [PDF]

Front Microbiol
Wang K, Liu X, Huang H, Suo M, Wang J, Liu X, Zhang J, Chen X, Li Z.   +8 more
europepmc   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

The impact of lipidome on intervertebral disk degeneration, low back pain, and sciatica: a Mendelian randomization study. [PDF]

Sci Rep
Pang ZY, Zhu YB, Hu JX, Li XX, Gao YJ, Wang YY, Zhou Q, Li P.   +7 more
europepmc   +1 more source