Results 181 to 190 of about 778,589 (272)

BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration. [PDF]

Aging Cell
Zhang G, Li L, Yang Z, Cao Z, Hu X, Wang Y, Kang X.   +6 more
europepmc   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari, Mallory Pine, Viktoriya Sapkalova, Emily Chan Brodowsky, Charles R. Powell, Ramzy T. Burns   +5 more
wiley   +1 more source

A Compact Annular Electrostatic Clutch Joint: Dynamic Response Modeling and Time‐Sharing Control for Underactuated Robots

SmartBot, EarlyView.
Electrostatic clutches offer programmable variable stiffness for multi‐DOF robots, but their continuous motion is usually bottlenecked by spatial constraints and detachment delays. Here, the authors report a compact annular electrostatic clutch joint with a biphasic amplitude‐frequency modulation strategy to rapidly mitigate residual polarization ...
Haochen Yong, Jian Wang, Zhisheng Xia, Zhexuan Li, Han Ding, Zhigang Wu   +5 more
wiley   +1 more source

Auto-immune Response in Degenerated Lumbar Disk

Yonsei Medical Journal, 1981
N H, Kim, E S, Kang, C D, Han, J D, Kim, C H, Kim   +4 more
openaire   +2 more sources

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

Small Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez, Akshat Joshi, Saeed Safari, Leticia A. M. de Carvalho, Kevin S. Muller, Uijin Kim, Luciana P. Cartarozzi, Meenakshi Kamaraj, Menekse Ermis, Natan R. de Barros, Alexandre L. R. de Oliveira   +10 more
wiley   +1 more source

Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy. [PDF]

JOR Spine
Xu T, Zhao H, Li J, Fang X, Wu H, Hu W.
europepmc   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

The role of micronutrients and serum metabolites in intervertebral disk degeneration: insights from a Mendelian randomization study and mediation analysis. [PDF]

Front Nutr
Jiang N, Wang Q, Jiang J, Li L.
europepmc   +1 more source

Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro‐Osteitis Disease Activity From a Phase 3 Brodalumab Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki, Manabu Arai, Junko Ochi, Mona Uchida‐Yamada, Masahiro Hashimoto, Mitsuhiro Akiyama, Yuko Kaneko, Yasumasa Kanai, Masahiro Jinzaki   +8 more
wiley   +1 more source

Therapeutic effect and mechanism of Yougui Wan in rats with intervertebral disk degeneration. [PDF]

J Orthop Surg Res
Ma S, Liu K, Yang JY, Huang RJ, Yu D.
europepmc   +1 more source